Renjian's thesis, Neuroprotective microRNAs combat HIV associated neurocognitive disorder (HAND) pathogenesis, states that nearly more than half of individuals living with HIV-1 infection present with some degree of neuronal impairment. Since, currently, no treatment is available to prevent or treat HAND, devising a method to manage HAND can help to improve the quality of life in HIV-1 positive population.
Harley's thesis, PrEP Awareness in Men Who Have Sex with Men (MSM) and Transgender Women Who Sought Services from the Allegheny County Health Department HIV/STD Clinic, 2016-2017, aims to provide insight into PrEP awareness in Allegheny County, PA among MSM, transgender women, and gender non-conforming individuals who were assigned a sex of male at birth attending the Allegheny County Health Department (ACHD) HIV/STD clinic.
Matt's findings in his thesis, Impact of Zika Virus on Human Dendritic Cells, contribute to our understanding of basic ZIKV : DC interactions, and may help to provide a better understanding of ZIKV pathogenesis leading towards the development of effective interventions to protect and treat those who may become exposed to ZIKV.
Abigail's essay, Baby and me, without Hep C: An early intervention education campaign to better the outcomes of HCV in mothers and neonates, examines the need to intervene to improve birth outcomes and improve postpartum HCV treatment adherence in women with SUD.
Bethany's thesis, Heme-induced acute lung injury by inflammasome activation in vascular endothelium, includes findings that could decrease morbidity among patients and improve the overall health of the public.
Megan's Essay, Validation of a real-time polymerase chain reaction assay for sensitive quantification of Francisella tularensis strains, hopes to further vaccine development for an extremely infectious disease in humans and animals.
The objective of Emily's thesis, Multidrug-resistant organisms (MDRO): Cost-effective analysis of horizontal vs. vertical surveillance, is to compare focused enhanced surveillance for populations at high-risk for MDRO colonization to the current vertically oriented (organism focused) surveillance strategy. A cost-effective analysis will be performed to determine which approach is more economical.
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