Pitt Public Health Students

Flatten the Curve

The University of Pittsburgh Graduate School of Public Health
is a top-ranked, internationally respected center of learning
and research that prepares students to influence public health
practices and care across the country and around the world.

Explore the school                   Coronavirus response

 

BCHS alum Arnold on harm-reduction during the coronavirus shutdown

PHILADELPHIA INQUIRER/SPOTLIG...
BCHS alum Arnold on harm-reduction during the coronavirus shutdown

PHILADELPHIA INQUIRER/SPOTLIGHT PA - At Prevention Point Pittsburgh, staff have been trying to raise awareness of COVID-19 for weeks. “If someone shows symptoms, they’re given gloves, a face mask, and extra harm reduction supplies so they can self-quarantine,” said executive director Aaron Arnold (... (03/31/2020)

Angus comments on top 10 ICU must-dos for COVID-19

MEDSCAPE - In an editorial in...
Angus comments on top 10 ICU must-dos for COVID-19

MEDSCAPE - In an editorial in the Journal of the American Medical Association issued just days after these new guidelines, Derek C. Angus, HPM distinguished professor and associate editor with JAMA, and his colleague Lamontagne of Canada say these "represent an excellent first step toward optimal, ... (03/31/2020)

Pitt Public Health updates FRED model forecasting as state sees lower rate of hospitalizations than China

KDKA – When will we see a COV...
Pitt Public Health updates FRED model forecasting as state sees lower rate of hospitalizations than China

KDKA – When will we see a COVID-19 peak? Health Secretary Rachel Levine said they’re working with Pitt’s FRED researchers to update information. Modeling infectious diseases is complex, and there are several impacting factors like how the disease is spread, the effects of social distancing, and the... (03/31/2020)

Wenzel on the burning problem of America’s sugar cane growers

BLOOMBERG QUINT - Sally Wenze...
Wenzel on the burning problem of America’s sugar cane growers

BLOOMBERG QUINT - Sally Wenzel, EOH professor and director of Pitt Medical Center's Asthma Institute, says that “The only way to answer the question” as to whether sugarcane burning is the direct cause of the respiratory issues that residents experience “is with a better level of granularity—to do ... (03/28/2020)

Pitt Public Health is part of Wolf’s “army of medical professionals” to address COVID-19 crisis

PUBLICSOURCE - Gov. Wolf said...
Pitt Public Health is part of Wolf’s “army of medical professionals” to address COVID-19 crisis

PUBLICSOURCE - Gov. Wolf said the state is ramping up efforts to expand capacity in the state’s healthcare system in anticipation of a spike in COVID-19 cases. He added that the state has enough capacity to handle all of its COVID-19 cases if the state’s efforts to socially isolate individuals are ... (03/28/2020)

 

Mon
3/23
Academic Calendar Notice
Fall 2020 Registration Begins Academic Calendar Notice
Fall 2020 Registration Begins
Mon 3/23 to Thu 7/2


Registration for Fall 2020 (term 2211) begins for all students. 

Mon
3/23
Academic Calendar Notice
Fall 2020 Add/Drop Begins Academic Calendar Notice
Fall 2020 Add/Drop Begins
Mon 3/23 to Fri 9/4


Add/drop begins for Fall 2020 (term 2211)

Wed
4/1
Pitt Public Health Event
Grand Rounds CANCELED - Dean's Day Student Poster SessionsGrand Rounds CANCELED - Dean's Day Student Poster Sessions Pitt Public Health Event
CANCELED - Dean's Day Student Poster Sessions
Wed 4/1 to Fri 4/3
Public Health Commons (1st floor)

Our annual showcase of student research, the Pitt Public Health Dean’s Day poster showcase will not be held this spring, either live or virtually. 

Thu
4/2
Career Services Event
SEC & ACC Virtual Career FairSEC & ACC Virtual Career Fair Career Services Event
SEC & ACC Virtual Career Fair
Thu 4/2 9:00AM - 6:00PM


The University of Pittsburgh Career Center invites all graduate students to attend the SEC & ACC Virtual Career Fair on Thursday, April 2nd from 9am-6pm. Meet with recruiters online and interact with employers seeking talent across all disciplines and degrees.

Thu
4/2
EOH Journal Club
Human & mouse single-nucleus transcriptomics reveal TREM2-dependent & TREM2-independent - ONLINE EOH Journal Club
Human & mouse single-nucleus transcriptomics reveal TREM2-dependent & TREM2-independent - ONLINE
Thu 4/2 11:00AM - 12:00PM


Join Zoom Meeting - https://pitt.zoom.us/j/356770679 Meeting ID: 356 770 679

Presenter: Yi Lu

Paper: Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease

Authors: Yingyue Zhou, Wilbur M. Song, Prabhakar S. Andhey, et Al.

Abstract:
Glia have been implicated in Alzheimer’s disease (AD) pathogenesis. Variants of the microglia receptor triggering receptor expressed on myeloid cells 2 (TREM2) increase AD risk, and activation of disease-associated microglia (DAM) is dependent on TREM2 in mouse models of AD. We surveyed gene-expression changes associated with AD pathology and TREM2 in 5XFAD mice and in human AD by single-nucleus RNA sequencing. We confirmed the presence of Trem2-dependent DAM and identified a previously undiscovered Serpina3n+C4b+ reactive oligodendrocyte population in mice. Interestingly, remarkably differential phenotypes were evident in human AD. Microglia signature was reminiscent of IRF8-driven reactive microglia in peripheral- nerve injury. Oligodendrocyte signatures suggested impaired axonal myelination and metabolic adaptation to neuronal degeneration. Astrocyte profiles indicated weakened metabolic coordination with neurons. Notably, the reactive phenotype of microglia was less evident in TREM2-R47H and TREM2-R62H carriers than in non-carriers,

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