My areas of expertise are in cardiovascular and environmental epidemiology and I have authored over 220 peer reviewed articles and book chapters devoted to the subjects. I am a fellow of the American Heart Association and the Council on Epidemiology and Prevention.
As an environmental epidemiologist with more than 35 years of experience, my work has centered upon both case-control as well as cohort studies involved with chronic and acute health effects of ambient air pollution (PM2.5 and air toxics). From 2005 until 2014, I was the director of one of five CDC Academic Centers for Excellence in Environmental Public Health Tracking at the University of Pittsburgh. I have been the major advisor and mentor to over 100 doctoral and masters’ students in this area and a founding member of the International Society for Environmental Epidemiology. I served as its secretary treasurer for four years. I conducted the Three Mile Island Follow-up study, the only 20-year cancer mortality and incidence cohort study in follow-up of 31,000 individuals exposed following the Three Mile Island Nuclear accident (1979- 1999) which occurred on March 29, 1979. (EHP, 2000, 2003).
For the last 15 years my focus is largely in studying the relationship of environmental and occupational exposures and the risk of neurodegenerative/neurodevelopmental disorders such as childhood autism, dementia, as well as ALS (Amyotrophic Lateral Sclerosis), a disease fatal disease with few identified risk factors. I serve as the PI on a retrospective cohort investigation using the Women’s Health Initiative cohort of 161,000 women considering long-term exposure to PM constituents and other air toxics and risk of ALS. I continue to complete work on an NIEHS investigation, Identification and Characterization of Potential Environmental Risk Factors for ALS Using the ATSDR ALS Registry Cases and a Control Population. The aim of this investigation is to utilize the ATSDR/ALS registry to conduct a case control study of environmental and personal risk factors for ALS. Most recently, I have also collaborated on a Pennsylvania Department of Health study on the Health Effects of Unconventional Gas Development in SW Pennsylvania. I remain involved with the CDC in their ALS registry and in the investigation of occupation and residential pesticide exposure and risk of ALS.
- Bethany College - BS Biology, 1969
- University of Pittsburgh - MPH Epidemiology, 1971
- University of Pittsburgh - DrPH Epidemiology, 1976
- Fellow of the American Heart Association, Council on Epidemiology and Prevention, 2001 to present
- Geospatial Mapping and Spatial Analysis in Epidemiology 2221
- Introduction to Environmental Epidemiology 2223
- 2022 Recipient of the APHA John Snow Award in Epidemiology for outstanding contributions to epidemiology and public health
- Talbott EO, Youk AO, McHugh KP, Shire JD, Zhang A, Murphy BP, Engberg RA. Mortality among the residents of the Three Mile Island accident area: 1979-1992. Environ Health Perspect. 2000 Jun:108(6):545-52. PubMed PMID: 10856029. PubMed Central PMCID: PMC1638153.
- Talbott EO, Youk AO, McHugh-Pemu KP, Zborowski JV. Long-term follow-up of the residents of the Three Mile Island accident area: 1979-1998. Environ Health Perspect. 2003 Mar;111(3):341-8. PubMed PMID: 12611664. PubMed Central PMCID: PMC1241392.
- Han YY, Youk AO, Sasser H, Talbott EO. Cancer incidence among residents of the Three Mile Island accident area: 1982-1995. Environ Res. 2011 Nov:111(8):1230-5. PubMed PMID: 21855866.
- Talbott EO, Marshall LP, Rager JR, Arena V, Sharma RK, Stacy SL. Air toxics and the risk of autism spectrum disorder: The results of a population based case control study in Southwestern Pennsylvania. Environ Health, Oct. 6th 2015. 14(1): p. 80. doi:10.1186/s12940-015-0064-1
- Eaglehouse YL, Talbott EO, Chang Y, Kuller LH, Participation in Physical Activity and Risk for Amyotrophic Lateral Sclerosis Mortality Among Postmenopausal Women. JAMA Neurol. 2016 Jan 19:1-9. doi: 10.1001/jamaneurol.2015.4487, PMID:26783702
- Malek AM, Arena VC, Song R, Whitsel EA, Rager JR, Stewart J, Yanosky JD, Liao D, Talbott EO. Long-term air pollution and risk of amyotrophic lateral sclerosis mortality in the Women's Health Initiative cohort. Environ Res. 2023 Jan 1;216(Pt 1):114510. doi: 10.1016/j.envres.2022.114510.
- Talbott EO, Rager JR, Brink LA, Bilonick RA, Benson SM, Wu W. A case-crossover analysis of the impact of PM(2.5) on cardiovascular disease hospitalizations for selected CDC tracking states. Environmental research. 2014; 134:455-65. PubMed [journal] PMID: 2527776
- DePerrior S, Rager JR, Gentile D, Talbott EO. The Relationship between Pollen, Air Pollution, and Asthma Exacerbations in Children in Allegheny County, Pennsylvania: A Case-Crossover Analysis. Arch Epidemiol 5: 148. Published 2021 January 13. DOI: 10.29011/2577-2252.100048.
- Talbott EO, Malek AM, Arena VC, Wu F, Steffes K et al.: Case-control study of environmental toxins and risk of amyotrophic lateral sclerosis involving the national ALS registry, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 09 Apr 2024 DOI: 10.1080/21678421.2024.2336108