My research is broadly based on the application of non-invasive subclinical vascular measures to the study of the natural history and prevention of CVD. As co-director (2006-2012) and director (December 2012-present) of the University of Pittsburgh Ultrasound Research Lab, I have collaborated on the application of early markers of vascular aging for >25 NIH-funded observational and intervention studies, including study design and implementation, oversight of collection of primary and secondary vascular outcome measures, data management and analyses of these vascular measures, and interpretation of these data for presentation and >120 peer-reviewed publications. I am particularly interested and actively involved in research on vascular aging in women and in investigating the role of obesity, related cardiometabolic disturbances and social determinants of health in the development and progression of subclinical CVD. I am co-director of the CVD Epidemiology T32 training program and actively mentor students and trainees at the master's, doctoral and post-doctoral level.
1991 | Bryn Mawr College, Bryn Mawr, PA | BA Chemistry
1998 | University of Pittsburgh, Pittsburgh, PA | PhD Epidemiology
2001 | University of Pittsburgh,Pittsburgh, PA | Post-doctoral training in CVD Epidemiology
EPIDEM 2152: Workshop in Cardiovascular Disease Epidemiology (2007-2012, Co-Instructor; 2012- Present, Instructor)
EPIDEM 2150: Epidemiology Cardiovascular Diseases (2011-Present, Guest Lecturer)
EPIDEM 2170: Chronic Disease Epidemiology (Fall 2020, Associate Instructor; Fall 2021, Co-Instructor)
BCHS 2526: Health Equity Research Methods (2015-2019, 2021 Guest Lecturer)
CVD Epidemiology Journal Club (2007- Present, Co-Instructor)
Co-Director, CVD Training Program (2012-Present)
Director, Health Equity Certificate Program
A complete list of published work can be found in MyBibliography
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Cooper JN, Columbus ML, Shields KJ, Asubonteng J, Meyer ML, Sutton-Tyrrell K, Goodpaster BH, Delany JP, Jakicic JM, Barinas-Mitchell E. Effects of an intensive behavioral weight loss intervention consisting of caloric restriction with or without physical activity on common carotid artery remodeling in severely obese adults. Metabolism. 2012 Nov; 61(11): 1589-97. PMID: 22579053. (senior author) *
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Thurston RC, Chang Y, Barinas-Mitchell E, Jennings JR, Landsittel DP, Santoro N, von Känel R, Matthews KA. Menopausal hot flashes and carotid intima media thickness among midlife women. Stroke 2016 Dec; 47(12):2910-2915. PMID: 27834746; PMCID: PMC5134903.
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Cortes YI, Catov JM, Brooks M, Harlow SD, Isasi CR, Jackson EA, Matthews KA, Thurston RC, Barinas-Mitchell E. History of Adverse Pregnancy Outcomes, Blood Pressure, and Subclinical Vascular Measures in Late Midlife: SWAN (Study of Women’s Health Across the Nation). J Am Heart Assoc. 2018;7(1). PubMed PMID: 29288157; PubMed CentralPMCID: PMC5778964. (senior author)*
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Duan C, Talbott EO, Brooks MM, Park SK, Broadwin R, Matthews KA, Barinas-Mitchell E. Five-year exposure to PM2.5 and ozone and subclinical atherosclerosis in late midlife women: The Study of Women's Health Across the Nation. Int J Hyg Environ Health. 2019 Mar;222(2):168-176. PMID: 30236459; PubMed Central PMCID: PMC6408975. (senior author) *
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Barinas-Mitchell E, Duan C, Brooks M, El Khoudary SR, Thurston R, Matthews K, Jackson EA, Lewis TT, Derby CA. Cumulative CVD risk factor burden during the menopause transition and late midlife subclinical vascular disease: Does race/ethnicity matter? JAHA. 2020 Feb 18; 9(4):e013876. PMID: 32063114. PMCID: PMC7070180.
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Lewis TT, Van Dyke ME, Matthews KA, Barinas-Mitchell E. Race/Ethnicity, Cumulative Midlife Loss and Carotid Atherosclerosis in Middle-Aged Women. Am J Epidemiol. 2021 Apr 6; 190(4):576-587. PMID: 33034337 PMCID: PMC8024052.
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Taylor C, Kline CE, Rice TB, Duan C, Newman AB, Barinas-Mitchell E. Snoring severity is associated with carotid vascular remodeling in young adults with overweight and obesity. Sleep Health 2021 Apr; 7(2): 161-167. PMID: 33402252. PMCID: PMC8084936. (senior author) *
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Barinas-Mitchell, E, Xiao Yang, Karen A. Matthews, Mindy L. Columbus, Charles J. George, Edit Dósa, MD, Eniko Kiss, Krisztina Kapornai, Rhobert Evans, Maria Kovacs. Childhood-onset depression and arterial stiffness in young adulthood. Journal of Psychosomatic Research 2021 Jun 14; kaab046. DOI: 10.1093/abm/kaab046. PMID: 34124743. PMCID: PMC8338846. DOI: 10.1016/j.jpsychores.2021.110551.
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Fujiyoshi A, Zaid M, Barinas-Mitchell E. Is Measuring Risk Marker Progression Useful for Cardiovascular Disease Prediction? Cerebrovasc Dis. 2021;50:752-755. PMID: 34350872. DOI: 10.1159/000517869.
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Schiff MD, Barinas-Mitchell E, Brooks MM, Mair CF, Méndez DD, Naimi AI, Hedderson M, Janssen I, Fabio A. Longitudinal Exposure to Neighborhood Concentrated Poverty Contributes to Differences in Adiposity in Midlife Women. J Womens Health (Larchmt). 2024 Jul 1. doi: 10.1089/jwh.2023.1156. PMID: 38946622.
