Alongside Principle Investigator Adrian Lee of the Institute for Precision Medicine, George Tseng has been awarded a prestigious $3 million, five-year R01 grant for the groundbreaking project "Single-cell congruence evaluation and selection of cancer models towards precision medicine."
The project represents a major collaborative effort, bringing together some of the brightest minds in the field of cancer research. Tseng will work alongside esteemed co-investigators including Biostatistics Faculty Jiebiao Wang, Gong Tang, and Wei Chen. Each researcher brings a unique skill set to a collaboration that will push the boundaries of cancer model development.
The core of their work leverages the latest advancements in omics and single-cell technologies to develop models that are more representative of actual human tumors. These technologies will allow the research team to evaluate cancer models with unprecedented precision, identifying those that most closely match the complexities and variabilities of human cancers. By using these enhanced models, they hope to address one of the most critical challenges in cancer research—creating models that accurately predict how tumors will respond to treatment.
Precision medicine is the future of cancer treatment, and this project aims to enhance personalized medicine by selecting cancer models that fit more closely with individual tumor profiles This will improve not only the accuracy of cancer research but also the effectiveness of drug discovery, potentially leading to better-targeted therapies and more successful outcomes for patients. This is a vital step toward making personalized, tailored treatment a reality for more patients.
For Tseng and the rest of the team, the award provides more than financial feasibility, but is also an encouragement to continue innovative work that has the potential to change the course of cancer treatment forever.
-Calvin Dziewulski