I am a Professor in the Infectious Disease Division and Director of the Center for Genomic Epidemiology. My research has focused on the epidemiology and genomic epidemiology of important pathogens including Streptococcus pneumoniae, group B Streptococcus, Neisseria meningitidis, methicillin-resistant Staphylococcus aureus, Clostridium difficile, SARS-CoV-2 and other respiratory viruses. A major focus of my research is methods for enhanced detection of hospital-acquired transmission of bacterial and viral pathogens using whole genomic sequencing surveillance and data mining of the electronic health record. I also am the Program Director of three NIH training grants: 1) A T32 program on antimicrobial resistance 2) a D43 international training grant on HIV infection in Mozambique, and 3) a D43 international training grant on public health genomics in South Africa.
BA, University of Pennsylvania, Philadelphia, PA, 1978
MD, Emory University School of Medicine, Atlanta, GA, 1982
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Marshall GS, McCormick ZL, Johns JS, Verduzco-Gutierrez M, Herrera-Restrepo O, Harrison LH. Understanding the Sequelae of Invasive Meningococcal Disease in the United States. Infect Dis Ther. 2024 Aug 30;.
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Cho ST, Mills EG, Griffith MP, Nordstrom HR, McElheny CL, Harrison LH, Doi Y, Van Tyne D. Evolution of extended-spectrum β-lactamase-producing ST131 Escherichia coli at a single hospital over 15 years. Sci Rep. 2024 Aug 26;14(1):19750.
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Mills EG, Smith AB, Griffith MP, Hewlett K, Pless L, Sundermann AJ, Harrison LH, Zackular JP, Van Tyne D. Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium. medRxiv. 2024 Aug 3;.
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Wateska AR, Nowalk MP, Altawalbeh SM, Lin CJ, Harrison LH, Schaffner W, Zimmerman RK, Smith KJ. Changes in the cost-effectiveness of pneumococcal vaccination and of programs to increase its uptake in U.S. older adults. J Am Geriatr Soc. 2024 Aug;72(8):2423-2433.
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Nachega JB, Sam-Agudu NA, Ogoina D, Mbala-Kingebeni P, Ntoumi F, Nakouné E, Njouom R, Lewis RF, Gandhi M, Rosenthal PJ, Rawat A, Wilson LA, Kindrachuk J, Liesenborghs L, Mills EJ, Preiser W, Rimoin AW, Sullivan NJ, Peeters M, Delaporte E, Baxter C, Harrison L, Hermans MP, Mohr EL, Gonsalves G, Ndembi N, Zumla A, Muyembe-Tamfum JJ. The surge of mpox in Africa: a call for action. Lancet Glob Health. 2024 Jul;12(7):e1086-e1088.
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Andrejko KL, Gierke R, Rowlands JV, Rosen JB, Thomas A, Landis ZQ, Rosales M, Petit S, Schaffner W, Holtzman C, Barnes M, Farley MM, Harrison LH, McGee L, Chochua S, Verani JR, Cohen AL, Pilishvili T, Kobayashi M. Effectiveness of 13-valent pneumococcal conjugate vaccine for prevention of invasive pneumococcal disease among children in the United States between 2010 and 2019: An indirect cohort study. Vaccine. 2024 Jun 11;42(16):3555-3563.
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Karunakaran S, Pless LL, Ayres AM, Ciccone C, Penzelik J, Sundermann AJ, Martin EM, Griffith MP, Waggle K, Hodges JC, Harrison LH, Snyder GM. Impact of discontinuation of contact precautions on surveillance- and whole genome sequencing-defined methicillin-resistant Staphylococcus aureus healthcare-associated infections. Antimicrob Steward Healthc Epidemiol. 2024;4(1):e97.
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Valek AL, Srinivasa VR, Ayres AM, Cheung S, Harrison LH, Snyder GM. Incidence and transmission associated with respiratory viruses in an acute care facility: An observational study. Infect Control Hosp Epidemiol. 2024 Jun;45(6):774-776.
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Altawalbeh SM, Wateska AR, Nowalk MP, Lin CJ, Harrison LH, Schaffner W, Zimmerman RK, Smith KJ. Pneumococcal Vaccination Strategies in 50-Year-Olds to Decrease Racial Disparities: A US Societal Perspective Cost-Effectiveness Analysis. Value Health. 2024 Jun;27(6):721-729.
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Sundermann AJ, Rangachar Srinivasa V, Mills EG, Griffith MP, Evans E, Chen J, Waggle KD, Snyder GM, Pless LL, Harrison LH, Van Tyne D. Genomic sequencing surveillance of patients colonized with vancomycin-resistant Enterococcus (VRE) improves detection of hospital-associated transmission. medRxiv. 2024 May 3.