IDM Department News

Nagy: 2019 Early Career Excellence Award

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Annie Nagy (IDM ’10) is the maternal and child health program administrator at the Allegheny County Health Department where she uses current public health science and evidence-based practices to manage the weC.A.R.E. and Healthy Families Allegheny programs. Nagy analyzes health information to assist in program implementation and establishes community relationships to promote and support the MCH Program’s strategic plan.  

Dean's Day 2019 IDM departmental award recipients

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Department of Infectious Diseases and Microbiology awards during our annual Dean's Day student research competition were given to Lindsay Summers (MPH '21), and Roberta Reis (PhD '19).  

Mailliard develops 'Swiss Army Knife' immunotherapy that kicks and kills HIV by exploiting a common virus

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ASPPH FRIDAY LETTER - In a first on the quest to cure human immunodeficiency virus, IDM's Robbie Mailliard and colleagues developed an all-in-one immunotherapy approach that not only kicks HIV out of hiding in the immune system, but also kills it. The key lies in immune cells designed to recognize an entirely different virus.   

Mailliard and Rinaldo on the quest to cure HIV using immunotherapy

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INFECTION CONTROL TODAY - IDM's Robbie Mailliard and Charles Rinaldo are on the quest to cure HIV using an all-in-one immunotherapy approach that not only kicks HIV out of hiding in the immune system but also kills it. The key lies in immune cells designed to recognize an entirely different virus.   

Marques finds that previous exposure to Dengue Fever protects against Zika

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90.5 WESA - Pitt researchers have found that previous exposure to Dengue Fever lowers the risk of infection from the Zika virus. “If we use currently approved Dengue vaccines or vaccines that are already close to become approved, you could boost Dengue responses... and could provide some degree of protection [against the Zika virus]” said IDM's Ernesto Marques, the study’s senior author.  

Burke on overdose deaths in Pittsburgh declining sharply

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PITTSBURGH TRIBUNE-REVIEW - "At this point, I'm not confident it is a permanent change for the good or if we're just returning to the expected curve," Dean Donald Burke said. "In our paper in Science a few months ago, we showed overdoses from all drugs, not just opioids, have been growing exponentially for 40 years. Occasionally it speeds up and slows down, but the growth curve always snapped back."   

Burke talks to The Economist about charting "the death curve"

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THE ECONOMIST - Charting overdose deaths shows an exponential curve increasing at a constant clip of 7.6% per year. Some modellers argue that the death curve might even continue its acceleration. “Anyone who tells me otherwise has to show me why that curve should bend now when it hasn’t in the face of the war on drugs and the rise and fall of other drugs,” says Dean Donald Burke.  

Meet Kelsey Simon (IDM '20), Dean's Scholar

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With a keen interest in biology and medicine since childhood, Kelsey Simon (IDM '20) planned to pursue a graduate degree in the hard sciences until a course requirement got her thinking about working at a population level. "I … really wanted a career where I could put all of these things together: biology, working with people, social/ethics, global health. An MPH combined all of these interests perfectly."  

Nachega finds drug-resistant TB cured with new approaches in conflict-affected region

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INFECTION CONTROL TODAY - A high proportion of multidrug-resistant tuberculosis cases can be cured in conflict-affected communities with molecular diagnostics, shorter treatment periods, and socioeconomic incentives, according to the results of a large, long-term study in the Democratic Republic of Congo led by IDM and EPI's Jean Nachega.   

Rister opens book store, continues making the public healthier

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PITTSBURGH POST-GAZETTE - On the surface, Adriene Rister (IDM) may seem to have made a dramatic career change, from dealing with infectious diseases for the state of Maine to running a children's book store. She sees the mission of both as bettering the community. "In a way, I like to think of this as part of public health...A bookstore should be a community hub, a place to gather around literacy and education, and a place to teach our kids abou... 

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Recent IDM Publications

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Rubio publishes thesis in Antimicrobial Agents and Therapy 

Rubio publishes thesis in Antimicrobial Agents and Therapy

Abigail Rubio (IDM '20) recently published In vitro Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa following Treatment-emergent Resistance to Ceftolozane-tazobactam, comparing the in vitro susceptibility of multidrug-resistant Pseudomonas aeruginosa isolates 34 collected before and af... (04/20/2021)

Zika-related adverse outcomes in a cohort of pregnant women with rash in Pernambuco, Brazil 

Zika-related adverse outcomes in a cohort of pregnant women with rash in Pernambuco, Brazil

Multiple authors on behalf of the Microcephaly Epidemic Research Group, including IDM's Ernesto Marques, found the frequency of microcephaly in their results is consistent with previous studies. In addition, as children were evaluated at a later age and repeatedly by different groups of specialists... (03/19/2021)

SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts 

SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts

Amy L. Hartman, Sham Nambulli, Cynthia M. McMillen, Alexander G. White, Natasha Louise Tilston-Lunel, Joseph R. Albe, Emily Cottle, Matthew D. Dunn, L. James Frye, Theron H. Gilliland, Emily L. Olsen, Katherine J. O’Malley, Madeline M. Schwarz, Jaime A. Tomko, Reagan C. Walker, Mengying Xia, Matthe... (11/17/2020)

Rapid 3D Enhanced Resolution Microscopy Reveals Diversity in Dendritic Spinule Dynamics, Regulation, and Function 

Rapid 3D Enhanced Resolution Microscopy Reveals Diversity in Dendritic Spinule Dynamics, Regulation, and Function

Colleen R. Zaccard, Lauren Shapiro, Maria D. Martin-de-Saavedra, Christopher Pratt, Kristoffer Myczek, Amy Song, Marc P. Forrest, Peter Penzes Dendritic spinules are thin protrusions, formed by neuronal spines, not adequately resolved by diffraction-limited light microscopy, which has limit... (11/17/2020)
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Prevalence and correlates of prep awareness and use among black men who have sex with men and women (MSMW) in the United States 

Prevalence and correlates of prep awareness and use among black men who have sex with men and women (MSMW) in the United States

AIDS AND BEHAVIOR - Friedman, MR, Sang, JM, Bukowski, LA, Chandler, CJ, Egan, JE, Eaton, LA, Matthews, DD, Ho, K, Raymond, HF, & Stall, R. found that PrEP awareness campaigns tailored for black men who have sex with men and women (MSMW), concomitant with STI-to-PrEP interventions, will facilitate g... (10/14/2019)
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Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions 

Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions

JOURNAL OF VIROLOGY - Using samples from participants in the Multicenter AIDS Cohort study, Garcia-Bates, Palma, Shen, Gambotto, Macatangay, Ferris, Rinaldo, and Mailliard showed that PD-1 activation plays a positive role in initiating the primary T cell response. But later blocking of that pathway... (12/13/2018)

Development of antibody biomarkers of long term and recent dengue virus infections 

Development of antibody biomarkers of long term and recent dengue virus infections

JOURNAL OF VIROLOGICAL METHODS - BURKE, MARQUES, and colleagues discuss anti-dengue NS1-specific IgG and IgG3 as potential biomarkers of long-term and recent (less than 6 months) DENV infections, respectively.  (06/14/2018)

Tradition and innovation in development of a Zika vaccine 

Tradition and innovation in development of a Zika vaccine

THE LANCET - MARQUES and BURKE comment about two Zika vaccines in clinical development and describe the challenges ahead. (06/14/2018)

IDM Videos

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Amanpour & Salk: Vaccine lessons from history (video) 

Amanpour & Salk: Vaccine lessons from history (video)

CNN — Christiane Amanpour discusses with IDM's Peter Salk the 97% drop in polio prevalence within a few years of initial vaccine adoption. In 1953, Dr. Peter Salk was one of the first to receive a polio vaccine—from none other than his father, Jonas Salk. They go on to discuss herd immunity and vac... (01/13/2021)
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"It's going to be a long road" - What IDM's Peter Salk thinks about COVID-19 

"It's going to be a long road" - What IDM's Peter Salk thinks about COVID-19

USA TODAY - Jonas Salk’s vaccine helped wipe polio from most of the world, something that many people hope will happen with the coronavirus vaccine. However, IDM's Dr. Peter Salk warns eradicating polio from the U.S. was a long and difficult journey, and he doesn’t expect eliminating COVID-19 will ... (12/29/2020)
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Biden coronavirus task force appointee Michael Osterholm discusses "The COVID Pandemic: The Evolving Reality" (video) 

Biden coronavirus task force appointee Michael Osterholm discusses "The COVID Pandemic: The Evolving Reality" (video)

In a special IDM Seminar, Michael T. Osterholm answers questions regarding the epidemiology of SARS-CoV-2 infection, public health strategies to reduce transmission, and thoughts on how the world will likely look one year from now. Osterholm was recently appointed to President-elect Biden's coronav... (12/17/2020)

Q&A: Peter Salk on the Lessons Learned from Vaccine Development History 

Q&A: Peter Salk on the Lessons Learned from Vaccine Development History

Peter Salk was 11 years old when a University of Pittsburgh team led by his father, the late Jonas Salk, created the inactivated poliovirus vaccine. The day of the 1955 announcement that the vaccine was safe, effective and potent, “everything just went crazy,” he recalls. “There were so many calls ... (11/17/2020)
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HIV-related stigma in healthcare settings during COVID-19 

HIV-related stigma in healthcare settings during COVID-19

As part of the Conversations about COVID-19 seminar series, Mackey Friedman of IDM and BCHS joins IDM's Sarah Krier to discuss how the COVID-19 pandemic is affecting the lives of people living with HIV including their beliefs and attitudes about their healthcare needs and experiences. (10/16/2020)
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