IDM Department News

40 Years of HIV Research: Grant Extends Lifetime of Pitt Men's Study

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UPMC NEWS - IDM Chair Charles Rinaldo recently received the news that a major study he directs to confidentially collect information on men living with HIV will be renewed into 2026 at nearly $4 million per year. The funding from the National Institutes of Health ensures that the Pitt Men's Study will survive into its fourth decade. But today, on HIV Long-Term Survivors Day, Rinaldo calls the remarkable milestone bittersweet.  

Cheyenne Annarumo awarded 2018-19 Bob Yee Scholarship

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Cheyenne Annarumo (IDM '20) was awarded a 2019 Bob Yee Public Health Scholarship. A native of Ellwood City, PA, Annarumo is pursuing an MPH with a concentration in infectious disease management, intervention, and community practice (MPH-MIC). She studied biology and was pre-med at Gannon University.   

Kelsey Simon awarded 2018-19 Bob Yee Scholarship

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Kelsey Simon (IDM '20) was awarded a 2019 Bob Yee Public Health Scholarship in recognition of academic excellence. A native of Buffalo, NY, Simon is pursuing an MPH in infectious disease pathogenesis, eradication, and laboratory practice (MPH-PEL). She holds an undergraduate biology degree from the University of Pittsburgh.   

Subramanian Thothathri awarded 2018-19 Bob Yee Scholarship

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Subramanian Thothathri (IDM '20) was awarded a 2019 Bob Yee Public Health Scholarship. A native of Chennai, India, Thothathri is pursuing an MS in infectious diseases and microbiology. He holds an undergraduate bioengineering degree from Sastra University.   

Four public health students chosen as 2019-20 Pittsburgh Schweitzer Fellows

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Four Pitt Public Health students have been selected as 2019-20 Pittsburgh Schweitzer Fellows. Inngide Osirus and Dzigbordi Kamasa-Quashie of IDM and Yamira Bell and Ariel Snell of the MMPH program will participate for a full year of experiential learning and direct service addressing the needs of disadvantaged citizens in southwest Pennsylvania. John Cordier (HPM '19) recently graduated from the Fellowship.  

2019 Celebration of Student Awards

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On April 27, 2019, Pitt Public Health celebrated recent graduates with awards given upon the culmination of a degree program. Delta Omega's honor society inductees were announced and outstanding thesis/essay and dissertation awards were conferred. Outstanding Student Awards were also given at both the master's and doctoral level, as well as Dean's Service Awards.   

Nagy: 2019 Early Career Excellence Award

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Annie Nagy (IDM ’10) is the maternal and child health program administrator at the Allegheny County Health Department where she uses current public health science and evidence-based practices to manage the weC.A.R.E. and Healthy Families Allegheny programs. Nagy analyzes health information to assist in program implementation and establishes community relationships to promote and support the MCH Program’s strategic plan.  

Dean's Day 2019 IDM departmental award recipients

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Department of Infectious Diseases and Microbiology awards during our annual Dean's Day student research competition were given to Lindsay Summers (MPH '21), and Roberta Reis (PhD '19).  

Mailliard develops 'Swiss Army Knife' immunotherapy that kicks and kills HIV by exploiting a common virus

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ASPPH FRIDAY LETTER - In a first on the quest to cure human immunodeficiency virus, IDM's Robbie Mailliard and colleagues developed an all-in-one immunotherapy approach that not only kicks HIV out of hiding in the immune system, but also kills it. The key lies in immune cells designed to recognize an entirely different virus.   

Mailliard and Rinaldo on the quest to cure HIV using immunotherapy

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INFECTION CONTROL TODAY - IDM's Robbie Mailliard and Charles Rinaldo are on the quest to cure HIV using an all-in-one immunotherapy approach that not only kicks HIV out of hiding in the immune system but also kills it. The key lies in immune cells designed to recognize an entirely different virus.   

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Recent IDM Publications

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Prevalence and correlates of prep awareness and use among black men who have sex with men and women (MSMW) in the United States 

Prevalence and correlates of prep awareness and use among black men who have sex with men and women (MSMW) in the United States

AIDS AND BEHAVIOR - Friedman, MR, Sang, JM, Bukowski, LA, Chandler, CJ, Egan, JE, Eaton, LA, Matthews, DD, Ho, K, Raymond, HF, & Stall, R. found that PrEP awareness campaigns tailored for black men who have sex with men and women (MSMW), concomitant with STI-to-PrEP interventions, will facilitate g... (10/14/2019)
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Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions 

Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions

JOURNAL OF VIROLOGY - Using samples from participants in the Multicenter AIDS Cohort study, Garcia-Bates, Palma, Shen, Gambotto, Macatangay, Ferris, Rinaldo, and Mailliard showed that PD-1 activation plays a positive role in initiating the primary T cell response. But later blocking of that pathway... (12/13/2018)

Development of antibody biomarkers of long term and recent dengue virus infections 

Development of antibody biomarkers of long term and recent dengue virus infections

JOURNAL OF VIROLOGICAL METHODS - BURKE, MARQUES, and colleagues discuss anti-dengue NS1-specific IgG and IgG3 as potential biomarkers of long-term and recent (less than 6 months) DENV infections, respectively.  (06/14/2018)

Tradition and innovation in development of a Zika vaccine 

Tradition and innovation in development of a Zika vaccine

THE LANCET - MARQUES and BURKE comment about two Zika vaccines in clinical development and describe the challenges ahead. (06/14/2018)

Zika virus displacement by a chikungunya outbreak in Recife, Brazil 

Zika virus displacement by a chikungunya outbreak in Recife, Brazil

PUBLIC LIBRARY OF SCIENCE - Magalhaes, Braga, Cordeiro, Oliveira, Castanha, Maciel, Amancio, Gouveia, Peixoto-deSilva Jr., Peixoto, Britto, Lima, Lima, and Marques detected the tail end of a Zika epidemic in 2015-16 which was displaced by a chikungunya epidemic. Few dengue cases were identified des... (06/14/2018)

Rift Valley fever in animals and humans: Current perspectives 

Rift Valley fever in animals and humans: Current perspectives

ANTIVIRAL RESEARCH - McMillen and Hartman discuss the historical role of Rift Valley Fever (RVF) as a biological weapon and conclude with an outline of the important unanswered questions for ongoing research into this important zoonotic disease. (06/11/2018)

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN 

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN

JOURNAL OF VIROLOGY - Delucia, Rinaldo, Rappocciolo demonstrate that the use of SIMV to decrease macrophage-mediated virus transfer should be considered for future HIV therapeutic development.  (05/18/2018)

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury 

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury

JOURNAL OF NEUROINFLAMMATION - Guha, Wagner, Ayyavoo conduct first study evaluating the potential role of Ng in the context of HIV-1 neropathogens and conclude that synaptic damage in HAND+ patients could be a result of abrogation of Ng through HIV-1 induced inflammation that dysregulates Ng-CaM in... (05/18/2018)

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IDM Videos

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The History and Future of COVID-19 

The History and Future of COVID-19

COVID-19 is one of three novel coronavirus outbreaks in the past 20 years that originated in animals. How is the current outbreak similar and different from the previous ones? What course will COVID-19 take in Pennsylvania?  IDM's  Amy Hartman  puts the current outbreak in perspective with what w... (05/12/2020)
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Rinaldo remembers unsung heroes: Pittsburgh men, decades-long study impact HIV/AIDS research 

Rinaldo remembers unsung heroes: Pittsburgh men, decades-long study impact HIV/AIDS research

U.S. NEWS & WORLD REPORT - For more than three decades, Pitt Men’s Study leaders have gathered with Pittsburgh men and women to remember those who have died and give thanks for the 1,743 men who have participated in the nation’s longest-running HIV/AIDS research project. IDM's Charles Rinaldo has l... (12/21/2019)
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Smith talks in-depth immunotherapy for lung cancer 

Smith talks in-depth immunotherapy for lung cancer

HOPE WITH ANSWERS - Discover in-depth information about immunotherapy for lung cancer through this conversation between Kellie Smith (IDM '13) of Johns Hopkins and patient advocate Lysa Buonanno, part of a video series providing the next level of information for patients to understand treatment opt... (08/12/2019)
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Hartman among researchers trying to prevent virus more dangerous than Zika (video) 

Hartman among researchers trying to prevent virus more dangerous than Zika (video)

WPXI - Pitt researchers are looking to lessons learned about Zika when preparing for the possibility of Rift Valley Fever virus, noting that it's important to develop therapies and vaccines now. "We saw the ffects of Zika when it got into a larger population and so our work highlights the need to r... (02/11/2019)
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IDM’s Rinaldo discusses HIV wonder drugs and curing HIV in 1998 World AIDS Day interview (VIDEO) 

IDM’s Rinaldo discusses HIV wonder drugs and curing HIV in 1998 World AIDS Day interview (VIDEO)

UPMC HEALTH NEWS – In the late 1990s, new and highly potent anti-HIV drugs emerged— including protease and reverse transcriptase inhibitors—which could for the first time control HIV infection. For this 1998 World AIDS Day, Pitt IDM AIDS researcher Charles Rinaldo and the late Bridget Murtagh of th... (07/17/2018)
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