IDM Department News

Microcephaly Found in Babies of Zika-Infected Mothers Months After Birth

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NEW YORK TIMES - Dr. Ernesto T. A. Marques Jr., an infectious disease specialist at the University of Pittsburgh and the Oswaldo Cruz Foundation in Recife, who was not involved in either study, said it could be that because of the initial fetal brain damage, “the necessary pathways and hormones that organize growth of the neonatal brain are not there anymore and the brain doesn’t grow.” 

Meet Joanna Shaw (IDM ’18), Dean’s Scholar

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Unsure of whether to pursue an MD, a PhD, or both, incoming Dean's Scholar JOANNA SHAW chose Pitt Public Health's Department of Infections Diseases and Microbiology to further develop her research and lab skills while she solidifies her research and career plans... 

Rodriguez serves on raccoon oral rabies vaccination team

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As a participant in the Allegheny County Health Department’s Pittsburgh Summer Institute (ACHD PSI), Samantha Rodriguez (IDM) helped to plan, execute, and review the county’s Raccoon Oral Rabies Vaccination (ORV) Program, as well as assisted with ORV distribution.  

Lowery conducts West Nile Virus surveillance with ACHD

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Joel Lowery (IDM ’17) assisted the ACHD in conducting its annual surveillance of West Nile Virus (WNV) in order to make informed decisions on vector control related to mosquitoes. In addition to WNV, the team monitored Aedes albopictus , a possible mosquito vector for the Zika virus. Lowery was responsible for setting traps, entering data, and shipping samples to the Pennsylvania Department of Environmental Protection for testing. He took awa... 

Jennifer Burwinkel awarded 2016-17 Bob Yee Scholarship 

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​ Jennifer Burwinkel (IDM '18) was awarded a 2016 Bob Yee Public Health Scholarship. A native of Cincinnati, OH, Burwinkel is pursuing an MS in infectious diseases and microbiology. She holds an undergraduate biology degree from Montreat College & Clearwater Christian College.  

Scott Chadwell awarded 2016-17 Bob Yee Scholarship 

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​ Scott Chadwell (IDM '17) was awarded a 2016 Bob Yee Public Health Scholarship. A native of Columbus, OH, Chadwell is pursuing a Master of Public Health degree with a concentration in infectious disease pathogenesis, eradication, and laboratory practice (MPH-PEL). He holds an undergraduate exercise science degree from the Ohio State University.  

Jerone Stoner awarded 2016-17 Bob Yee Scholarship

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​ Jerone Stoner (IDM '17) was awarded a 2016 Bob Yee Public Health Scholarship. A native of Chambersburg, PA, Stoner is pursuing a Master of Public Health degree with a concentration in infectious disease management, intervention, and community practice (MPH-MIC). He holds an undergraduate biochemistry & molecular biology degree from Dickinson College.  

There's No Vaccine Yet for CMV

Work on a vaccine for CMV has been going on for many years, said microbiologist Charles Rinaldo, PhD, an expert in cytomegalovirus in the Department of Infectious Diseases and Microbiology at Pitt Public Health. 

Revolutionary Acts: How the discussion of HIV risk matters for the health of Black men who have sex with men

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Derrick D. Matthews, assistant professor in the University of Pittsburgh Graduate School of Public Health’s Department of Infectious Diseases and Microbiology, focuses his research upon the disproportionate burden the HIV epidemic has on black gay, bisexual and other men who have sex with men (MSM) in the U.S....  

Doctor returns to Pittsburgh after trip To Brazil to study Zika virus

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PITTSBURGH (KDKA) — Ernesto Marques at the Pitt Center for Vaccine Research  recently traveled to Brazil  to study  Zika virus . In that time, the CDC announced a definitive relationship between Zika and microcephaly based on the timing, the virus in fluids and tissues, antibodies against the virus in the brains of these babies with small heads, and studies of cases and non-cases.   See full story  

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Recent IDM Publications

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Prevalence and correlates of prep awareness and use among black men who have sex with men and women (MSMW) in the United States 

Prevalence and correlates of prep awareness and use among black men who have sex with men and women (MSMW) in the United States

AIDS AND BEHAVIOR - Friedman, MR, Sang, JM, Bukowski, LA, Chandler, CJ, Egan, JE, Eaton, LA, Matthews, DD, Ho, K, Raymond, HF, & Stall, R. found that PrEP awareness campaigns tailored for black men who have sex with men and women (MSMW), concomitant with STI-to-PrEP interventions, will facilitate g... (10/14/2019)
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Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions 

Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions

JOURNAL OF VIROLOGY - Using samples from participants in the Multicenter AIDS Cohort study, Garcia-Bates, Palma, Shen, Gambotto, Macatangay, Ferris, Rinaldo, and Mailliard showed that PD-1 activation plays a positive role in initiating the primary T cell response. But later blocking of that pathway... (12/13/2018)

Development of antibody biomarkers of long term and recent dengue virus infections 

Development of antibody biomarkers of long term and recent dengue virus infections

JOURNAL OF VIROLOGICAL METHODS - BURKE, MARQUES, and colleagues discuss anti-dengue NS1-specific IgG and IgG3 as potential biomarkers of long-term and recent (less than 6 months) DENV infections, respectively.  (06/14/2018)

Tradition and innovation in development of a Zika vaccine 

Tradition and innovation in development of a Zika vaccine

THE LANCET - MARQUES and BURKE comment about two Zika vaccines in clinical development and describe the challenges ahead. (06/14/2018)

Zika virus displacement by a chikungunya outbreak in Recife, Brazil 

Zika virus displacement by a chikungunya outbreak in Recife, Brazil

PUBLIC LIBRARY OF SCIENCE - Magalhaes, Braga, Cordeiro, Oliveira, Castanha, Maciel, Amancio, Gouveia, Peixoto-deSilva Jr., Peixoto, Britto, Lima, Lima, and Marques detected the tail end of a Zika epidemic in 2015-16 which was displaced by a chikungunya epidemic. Few dengue cases were identified des... (06/14/2018)

Rift Valley fever in animals and humans: Current perspectives 

Rift Valley fever in animals and humans: Current perspectives

ANTIVIRAL RESEARCH - McMillen and Hartman discuss the historical role of Rift Valley Fever (RVF) as a biological weapon and conclude with an outline of the important unanswered questions for ongoing research into this important zoonotic disease. (06/11/2018)

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN 

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN

JOURNAL OF VIROLOGY - Delucia, Rinaldo, Rappocciolo demonstrate that the use of SIMV to decrease macrophage-mediated virus transfer should be considered for future HIV therapeutic development.  (05/18/2018)

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury 

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury

JOURNAL OF NEUROINFLAMMATION - Guha, Wagner, Ayyavoo conduct first study evaluating the potential role of Ng in the context of HIV-1 neropathogens and conclude that synaptic damage in HAND+ patients could be a result of abrogation of Ng through HIV-1 induced inflammation that dysregulates Ng-CaM in... (05/18/2018)

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IDM Videos

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The History and Future of COVID-19 

The History and Future of COVID-19

COVID-19 is one of three novel coronavirus outbreaks in the past 20 years that originated in animals. How is the current outbreak similar and different from the previous ones? What course will COVID-19 take in Pennsylvania?  IDM's  Amy Hartman  puts the current outbreak in perspective with what w... (05/12/2020)
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Rinaldo remembers unsung heroes: Pittsburgh men, decades-long study impact HIV/AIDS research 

Rinaldo remembers unsung heroes: Pittsburgh men, decades-long study impact HIV/AIDS research

U.S. NEWS & WORLD REPORT - For more than three decades, Pitt Men’s Study leaders have gathered with Pittsburgh men and women to remember those who have died and give thanks for the 1,743 men who have participated in the nation’s longest-running HIV/AIDS research project. IDM's Charles Rinaldo has l... (12/21/2019)
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Smith talks in-depth immunotherapy for lung cancer 

Smith talks in-depth immunotherapy for lung cancer

HOPE WITH ANSWERS - Discover in-depth information about immunotherapy for lung cancer through this conversation between Kellie Smith (IDM '13) of Johns Hopkins and patient advocate Lysa Buonanno, part of a video series providing the next level of information for patients to understand treatment opt... (08/12/2019)
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Hartman among researchers trying to prevent virus more dangerous than Zika (video) 

Hartman among researchers trying to prevent virus more dangerous than Zika (video)

WPXI - Pitt researchers are looking to lessons learned about Zika when preparing for the possibility of Rift Valley Fever virus, noting that it's important to develop therapies and vaccines now. "We saw the ffects of Zika when it got into a larger population and so our work highlights the need to r... (02/11/2019)
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IDM’s Rinaldo discusses HIV wonder drugs and curing HIV in 1998 World AIDS Day interview (VIDEO) 

IDM’s Rinaldo discusses HIV wonder drugs and curing HIV in 1998 World AIDS Day interview (VIDEO)

UPMC HEALTH NEWS – In the late 1990s, new and highly potent anti-HIV drugs emerged— including protease and reverse transcriptase inhibitors—which could for the first time control HIV infection. For this 1998 World AIDS Day, Pitt IDM AIDS researcher Charles Rinaldo and the late Bridget Murtagh of th... (07/17/2018)
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