IDM Department News

Rappocciolo presents research on cell cholesterol dysregulation in HIV non-progressors at 2018 Conference on Retroviruses and Opportunistic Infections

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IDM's GIOVANNA RAPPOCCIOLO presented at the Conference on Retroviruses and Opportunistic Infections on biomarkers and genetics of cell cholesterol dysregulation in HIV non-progressors. Co-authors include IDM faculty J MARTINSON and C RINALDO and recent doctoral graduate DIANA DELUCIA.   

Melody receives postdoctoral fellowship

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University of Texas Medical Branch-Galveston has offered KEVIN MELODY (IDM '17) a postdoctoral fellowship in a BSL-4 research group headed by Thomas Geisbert. Due to the security and proficiency needed to perform the work, Kevin will undergo extensive training before beginning high-containment pathogen-related research.  

Swan joins Cato Research

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"A great company in a great industry," says ZACHARY SWAN (IDM '16) who has recently secured a position as a Regulatory Affairs, Clinical Strategy Scientist at a CRO in the Research Triangle Park named Cato Research.  

Emerson Evans on detail with CDC

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Helping out with The United States President's Emergency Plan for AIDS Relief (PEPFAR) Country Operational Plan submission, EMERSON EVANS (IDM '12) is currently working in South Africa on detail with the CDC.  

Poston receives San-Pin Wang Award from the Chlamydia Basic Research Society

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The San-Pin Wang Award for the best graduate student oral presentation at the Chlamydia Basic Research Society 2017 conference was given to TAYLOR POSTON (IDM '17). This award was established in honor of the memory of Dr. San-Pin Wang and a cash prize was generously donated by the San-Pin Wang Endowment Fund.  

Farmartino: 2018 Early Career Excellence Award

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In 2012, a year before completing her MPH, CHRISTINA FARMARTINO (IDM ’13) was hired as executive director of The Open Door, which provides supportive housing and representative payee services to individuals living with HIV/AIDS—including active injection drug users—to improve their health and housing stability. Among other duties, Farmartino has raised more than $250,000 over three years in additional, diversified funding.  

Bowling presents paper at Chemical & Biological Defense Science & Technology Conference

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JENNIFER BOWLING (IDM '21) attended the Chemical & Biological Defense Science & Technology Conference to present her paper on “Influence of Sex on Protection Conferred by Vaccination with Attenuated Strains of Francisella tularensis in the Rabbit Model.”  

Grant named department's student representative

IDM's NICOLE GRANT has been nominated to serve as the student representative for the department. Grant will attend faculty meetings to provide a student perspective and bring student concerns to the table. Congratulations, Nicole!   

Malinauskas attends Oxford Nanopore Technologies Community Meeting

"The [meeting] was a tremendous opportunity for me to network and learn from other scientists in my field," said JENNA MALINAUSKAS (IDM). "I learned tips and tricks to sequencing during the hands on training portion, what resources are available to me as a researcher, and how to improve my science. The opportunity to become more involved in the scientific community will benefit me throughout my career and I'm excited to attend more conferences i... 

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques

JOURNAL OF IMMUNOLOGY - Wonderlich, Swan, Bissel, Hartman, Carney, O'Malley, Obadan, Santos, Walker, Sturgeon, Frye, Maiello, Scanga, Bowling, Duangkhae, Wiley, Flynn, Wang, Cole, Reed, Barratt-Boyes establish a new nonhuman primate disease model for evaluation of vaccine and therapeutic approaches to prevent and treat infection with highly pathogenic avian influenza viruses.   

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Recent IDM Publications

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Prevalence and correlates of prep awareness and use among black men who have sex with men and women (MSMW) in the United States 

Prevalence and correlates of prep awareness and use among black men who have sex with men and women (MSMW) in the United States

AIDS AND BEHAVIOR - Friedman, MR, Sang, JM, Bukowski, LA, Chandler, CJ, Egan, JE, Eaton, LA, Matthews, DD, Ho, K, Raymond, HF, & Stall, R. found that PrEP awareness campaigns tailored for black men who have sex with men and women (MSMW), concomitant with STI-to-PrEP interventions, will facilitate g... (10/14/2019)
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Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions 

Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions

JOURNAL OF VIROLOGY - Using samples from participants in the Multicenter AIDS Cohort study, Garcia-Bates, Palma, Shen, Gambotto, Macatangay, Ferris, Rinaldo, and Mailliard showed that PD-1 activation plays a positive role in initiating the primary T cell response. But later blocking of that pathway... (12/13/2018)

Development of antibody biomarkers of long term and recent dengue virus infections 

Development of antibody biomarkers of long term and recent dengue virus infections

JOURNAL OF VIROLOGICAL METHODS - BURKE, MARQUES, and colleagues discuss anti-dengue NS1-specific IgG and IgG3 as potential biomarkers of long-term and recent (less than 6 months) DENV infections, respectively.  (06/14/2018)

Tradition and innovation in development of a Zika vaccine 

Tradition and innovation in development of a Zika vaccine

THE LANCET - MARQUES and BURKE comment about two Zika vaccines in clinical development and describe the challenges ahead. (06/14/2018)

Zika virus displacement by a chikungunya outbreak in Recife, Brazil 

Zika virus displacement by a chikungunya outbreak in Recife, Brazil

PUBLIC LIBRARY OF SCIENCE - Magalhaes, Braga, Cordeiro, Oliveira, Castanha, Maciel, Amancio, Gouveia, Peixoto-deSilva Jr., Peixoto, Britto, Lima, Lima, and Marques detected the tail end of a Zika epidemic in 2015-16 which was displaced by a chikungunya epidemic. Few dengue cases were identified des... (06/14/2018)

Rift Valley fever in animals and humans: Current perspectives 

Rift Valley fever in animals and humans: Current perspectives

ANTIVIRAL RESEARCH - McMillen and Hartman discuss the historical role of Rift Valley Fever (RVF) as a biological weapon and conclude with an outline of the important unanswered questions for ongoing research into this important zoonotic disease. (06/11/2018)

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN 

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN

JOURNAL OF VIROLOGY - Delucia, Rinaldo, Rappocciolo demonstrate that the use of SIMV to decrease macrophage-mediated virus transfer should be considered for future HIV therapeutic development.  (05/18/2018)

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury 

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury

JOURNAL OF NEUROINFLAMMATION - Guha, Wagner, Ayyavoo conduct first study evaluating the potential role of Ng in the context of HIV-1 neropathogens and conclude that synaptic damage in HAND+ patients could be a result of abrogation of Ng through HIV-1 induced inflammation that dysregulates Ng-CaM in... (05/18/2018)

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IDM Videos

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The History and Future of COVID-19 

The History and Future of COVID-19

COVID-19 is one of three novel coronavirus outbreaks in the past 20 years that originated in animals. How is the current outbreak similar and different from the previous ones? What course will COVID-19 take in Pennsylvania?  IDM's  Amy Hartman  puts the current outbreak in perspective with what w... (05/12/2020)
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Rinaldo remembers unsung heroes: Pittsburgh men, decades-long study impact HIV/AIDS research 

Rinaldo remembers unsung heroes: Pittsburgh men, decades-long study impact HIV/AIDS research

U.S. NEWS & WORLD REPORT - For more than three decades, Pitt Men’s Study leaders have gathered with Pittsburgh men and women to remember those who have died and give thanks for the 1,743 men who have participated in the nation’s longest-running HIV/AIDS research project. IDM's Charles Rinaldo has l... (12/21/2019)
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Smith talks in-depth immunotherapy for lung cancer 

Smith talks in-depth immunotherapy for lung cancer

HOPE WITH ANSWERS - Discover in-depth information about immunotherapy for lung cancer through this conversation between Kellie Smith (IDM '13) of Johns Hopkins and patient advocate Lysa Buonanno, part of a video series providing the next level of information for patients to understand treatment opt... (08/12/2019)
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Hartman among researchers trying to prevent virus more dangerous than Zika (video) 

Hartman among researchers trying to prevent virus more dangerous than Zika (video)

WPXI - Pitt researchers are looking to lessons learned about Zika when preparing for the possibility of Rift Valley Fever virus, noting that it's important to develop therapies and vaccines now. "We saw the ffects of Zika when it got into a larger population and so our work highlights the need to r... (02/11/2019)
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IDM’s Rinaldo discusses HIV wonder drugs and curing HIV in 1998 World AIDS Day interview (VIDEO) 

IDM’s Rinaldo discusses HIV wonder drugs and curing HIV in 1998 World AIDS Day interview (VIDEO)

UPMC HEALTH NEWS – In the late 1990s, new and highly potent anti-HIV drugs emerged— including protease and reverse transcriptase inhibitors—which could for the first time control HIV infection. For this 1998 World AIDS Day, Pitt IDM AIDS researcher Charles Rinaldo and the late Bridget Murtagh of th... (07/17/2018)
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