IDM Department News

Nachega recognized by African Science Institutions

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The African Academy of Sciences elected IDM and EPI's Jean Nachega a fellow in recognition of his efforts to develop patient care, teaching, and research around epidemiology and infectious diseases in Africa. In addition, the Academy of Sciences of South Africa - which aims to provide evidence-based scientific advice on issues of public interest - named him a member-elect.  

Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions

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JOURNAL OF VIROLOGY - Using samples from participants in the Multicenter AIDS Cohort study, Garcia-Bates, Palma, Shen, Gambotto, Macatangay, Ferris, Rinaldo, and Mailliard showed that PD-1 activation plays a positive role in initiating the primary T cell response. But later blocking of that pathway can enhance the overall magnitude of the immune system’s ability to remember and respond to HIV.   

Hartman and team study tropical mosquito-borne virus linked to miscarriage, stillbirth in animals

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WESA-FM - Research suggests the Rift Valley Fever can affect developing human fetuses. IDM's Amy Hartman, along with first author Cynthia McMillen who is an IDM postdoc, chose to study Rift Valley’s effects on pregnant rats, since humans and rats have similar placental structures. They found that 65 percent of pups born to infected rats died, even when the mother rats appeared healthy.   

Frank on why, after more than 30 years, there is still no vaccine for HIV

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KDKA-AM - More than 30 years after HIV was uncovered there is still no AIDS vaccine, but IDM's Linda Frank, who heads the MidAtlantic AIDS Education and Training Center, says, “People who are uninfected can take anti-retrovirals to prevent them from getting HIV infected. This is so wonderful.” Frank says the new frontier in HIV treatment is in conjunction with diseases like hepatitis, sexually transmitted disease, and substance abuse.  

County project tackling AIDS and HIV reports fewer new cases

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POST GAZETTE - Allegheny County health officials are reporting progress in the fight against AIDS by reducing new HIV cases. A key part of this effort is education. The MidAtlantic AIDS Education and Training Center, led by Linda Frank, has been involved in efforts to fight AIDS for the past 30 years. The World AIDS Day 2018 conference “is about the new treatments and advancements to help us get to zero new cases,” says Frank.  

Student Noreen Chatta shares her analysis of endoscope procedures and bacterial cultures at APHA 2018

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APHA - Noreen Chatta (IDM) presented her research on Safety of Gastrointestinal (GI) Endoscopic Procedures at a Large Academic Medical Center during a poster symposium at APHA's 2018 annual meeting. In this study, she assessed and monitored the safety of endoscopic procedures using microbiologic cultures and electronic medical records, evaluating for 30-day microbiologic results after endoscopic procedures.  

Turning ideas into transformative action: Pitt Public Health students selected as Future Health Leaders

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Complex health issues are easy to determine, but finding solutions can be challenging. Three Pitt Public Health students, ASHLEY SIMENSON (EPI ’19), JESSICA SALERNO (IDM ’20), and KAITLYN SAAL-RIDPATH (HPM ’20) were chosen as part of the inaugural class of Future Health Leaders to present their ideas at the Milken Institute's Future of Health Summit 2018 in Washington DC.  

Simenson, Salerno, Saal-Ridpath selected for future health leaders program

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PITT WIRE - Three students from Pitt Public Health were selected for the inaugural class of The Milken Institute’s Future Health Leaders Program. The students, ASHLEY SIMENSON (EPI '19), JESSICA SALERNO (IDM '20), and KAITLYN SAAL-RIDPATH (HPM '20), are among a dozen of fellows selected nationwide. The program aims to give the students exposure to health leadership to help accelerate their future work tackling complex public health challenges.... 

Human immunodeficiency virus infection induces lymphoid fibrosis in the BM-liver-thymus-spleen humanized mouse model

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JOURNAL OF CLINICAL INVESTIGATION INSIGHT - Jasmine Samal, Samantha Kelly, Ali Na-Shatal, Abdallah Elhakiem, Antu Das, Ming Ding, Anwesha Sanyal, Phalguni Gupta, Kevin Melody, Brad Roland, Watfa Ahmed, Aala Zakir, and Moses Bility developed a potentially novel human immune system–humanized mouse model.  

Sundermann keeps asking 'why?'

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ALEX SUNDERMANN (IDM) is the featured MPH profile in the fall issue of Prevention Strategist, a magazine issued by the Association for Professionals in Infection Control and Epidemiology. When asked about the best advice he ever received, he said, 'keep asking 'why?'"  

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Recent IDM Publications

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Rubio publishes thesis in Antimicrobial Agents and Therapy 

Rubio publishes thesis in Antimicrobial Agents and Therapy

Abigail Rubio (IDM '20) recently published In vitro Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa following Treatment-emergent Resistance to Ceftolozane-tazobactam, comparing the in vitro susceptibility of multidrug-resistant Pseudomonas aeruginosa isolates 34 collected before and af... (04/20/2021)

Zika-related adverse outcomes in a cohort of pregnant women with rash in Pernambuco, Brazil 

Zika-related adverse outcomes in a cohort of pregnant women with rash in Pernambuco, Brazil

Multiple authors on behalf of the Microcephaly Epidemic Research Group, including IDM's Ernesto Marques, found the frequency of microcephaly in their results is consistent with previous studies. In addition, as children were evaluated at a later age and repeatedly by different groups of specialists... (03/19/2021)

SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts 

SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts

Amy L. Hartman, Sham Nambulli, Cynthia M. McMillen, Alexander G. White, Natasha Louise Tilston-Lunel, Joseph R. Albe, Emily Cottle, Matthew D. Dunn, L. James Frye, Theron H. Gilliland, Emily L. Olsen, Katherine J. O’Malley, Madeline M. Schwarz, Jaime A. Tomko, Reagan C. Walker, Mengying Xia, Matthe... (11/17/2020)

Rapid 3D Enhanced Resolution Microscopy Reveals Diversity in Dendritic Spinule Dynamics, Regulation, and Function 

Rapid 3D Enhanced Resolution Microscopy Reveals Diversity in Dendritic Spinule Dynamics, Regulation, and Function

Colleen R. Zaccard, Lauren Shapiro, Maria D. Martin-de-Saavedra, Christopher Pratt, Kristoffer Myczek, Amy Song, Marc P. Forrest, Peter Penzes Dendritic spinules are thin protrusions, formed by neuronal spines, not adequately resolved by diffraction-limited light microscopy, which has limit... (11/17/2020)
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Prevalence and correlates of prep awareness and use among black men who have sex with men and women (MSMW) in the United States 

Prevalence and correlates of prep awareness and use among black men who have sex with men and women (MSMW) in the United States

AIDS AND BEHAVIOR - Friedman, MR, Sang, JM, Bukowski, LA, Chandler, CJ, Egan, JE, Eaton, LA, Matthews, DD, Ho, K, Raymond, HF, & Stall, R. found that PrEP awareness campaigns tailored for black men who have sex with men and women (MSMW), concomitant with STI-to-PrEP interventions, will facilitate g... (10/14/2019)
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Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions 

Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions

JOURNAL OF VIROLOGY - Using samples from participants in the Multicenter AIDS Cohort study, Garcia-Bates, Palma, Shen, Gambotto, Macatangay, Ferris, Rinaldo, and Mailliard showed that PD-1 activation plays a positive role in initiating the primary T cell response. But later blocking of that pathway... (12/13/2018)

Development of antibody biomarkers of long term and recent dengue virus infections 

Development of antibody biomarkers of long term and recent dengue virus infections

JOURNAL OF VIROLOGICAL METHODS - BURKE, MARQUES, and colleagues discuss anti-dengue NS1-specific IgG and IgG3 as potential biomarkers of long-term and recent (less than 6 months) DENV infections, respectively.  (06/14/2018)

Tradition and innovation in development of a Zika vaccine 

Tradition and innovation in development of a Zika vaccine

THE LANCET - MARQUES and BURKE comment about two Zika vaccines in clinical development and describe the challenges ahead. (06/14/2018)

IDM Videos

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Amanpour & Salk: Vaccine lessons from history (video) 

Amanpour & Salk: Vaccine lessons from history (video)

CNN — Christiane Amanpour discusses with IDM's Peter Salk the 97% drop in polio prevalence within a few years of initial vaccine adoption. In 1953, Dr. Peter Salk was one of the first to receive a polio vaccine—from none other than his father, Jonas Salk. They go on to discuss herd immunity and vac... (01/13/2021)
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"It's going to be a long road" - What IDM's Peter Salk thinks about COVID-19 

"It's going to be a long road" - What IDM's Peter Salk thinks about COVID-19

USA TODAY - Jonas Salk’s vaccine helped wipe polio from most of the world, something that many people hope will happen with the coronavirus vaccine. However, IDM's Dr. Peter Salk warns eradicating polio from the U.S. was a long and difficult journey, and he doesn’t expect eliminating COVID-19 will ... (12/29/2020)
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Biden coronavirus task force appointee Michael Osterholm discusses "The COVID Pandemic: The Evolving Reality" (video) 

Biden coronavirus task force appointee Michael Osterholm discusses "The COVID Pandemic: The Evolving Reality" (video)

In a special IDM Seminar, Michael T. Osterholm answers questions regarding the epidemiology of SARS-CoV-2 infection, public health strategies to reduce transmission, and thoughts on how the world will likely look one year from now. Osterholm was recently appointed to President-elect Biden's coronav... (12/17/2020)

Q&A: Peter Salk on the Lessons Learned from Vaccine Development History 

Q&A: Peter Salk on the Lessons Learned from Vaccine Development History

Peter Salk was 11 years old when a University of Pittsburgh team led by his father, the late Jonas Salk, created the inactivated poliovirus vaccine. The day of the 1955 announcement that the vaccine was safe, effective and potent, “everything just went crazy,” he recalls. “There were so many calls ... (11/17/2020)
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HIV-related stigma in healthcare settings during COVID-19 

HIV-related stigma in healthcare settings during COVID-19

As part of the Conversations about COVID-19 seminar series, Mackey Friedman of IDM and BCHS joins IDM's Sarah Krier to discuss how the COVID-19 pandemic is affecting the lives of people living with HIV including their beliefs and attitudes about their healthcare needs and experiences. (10/16/2020)
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