NPR – Pitt Medical Center’s Derek Angus (BCHS ’92) said that while some worried that steroids could also prevent the body from fighting off the coronavirus, all the coordinated studies reached the same conclusion, which is, I guess we have to stop our trials. It is reassuring that we can get randomized trials executed successfully and rapidly in the face of a pandemic, and it definitely puts us on a sure footing.
LOS ANGELES TIMES – A comprehensive study from Iceland revealed that natural antibodies remained stable for four months, longer than was first thought. HPM’s Derek Angus (BCHS ’92), UPMC’s critical care chief, said that “will be encouraging for people working on vaccines.” He added that the infection fatality rate of 0.3 percent is in keeping with recent estimates here in the U.S.
POLITICO - The feedback: “Not only do voluntary discounts not last long, but discounts do nothing to address the prices of drugs that come out after any discount goes into place,” tweeted HPM’s Walid Gellad, director of the Center for Pharmaceutical Policy and Prescribing at the University of Pittsburgh. “Also, what is a 10 percent discount when list prices increases by 9.9 percent a year?”
NEW YORK TIMES – Many experts were bewildered about where a key statistic came from. HPM's Walid Gellad, who leads Pitt’s Center for Pharmaceutical Policy and Prescribing, said, “For the first time ever, I feel like official people in communications and people at the F.D.A. grossly misrepresented data about a therapy.” Millions will rely on the FDA' judgement. “That’s a problem if they’re starting to exaggerate data.”
REUTERS - HPM’s Derek Angus (BCHS '92) and Pitt's Erin McCreary coauthored a study editorial raising questions about whether some patients get more benefit from remdesivir than others and whether it matters if patients receive remdesivir and steroids together. It is still possible that remdesivir could improve recovery for millions of patients hospitalized with COVID-19, they added, but more research is needed before that becomes clear.
STAT - “The temporary reform due to Covid allowed telemedicine visits from a patient’s home, but it presumed that patients had access to the technology to engage in those visits,” said HPM’s Eric Roberts, paper co-author. “We’re showing that there’s a substantial number of Medicare beneficiaries who lack access to that technology… a very vulnerable population both in terms of their health profile and their economic profile.”
SLATE – Since January, researchers hoping to fight COVID-19 have designed a stunning 1,200 clinical trials, but the effort has been marked by disorder and disorganization, with huge financial resources wasted. Applying history lessons to today, HPM’s Walid Gellad, director of the Center for Pharmaceutical Policy and Prescribing, slammed U.S. leadership for failing to set a clear clinical trial agenda.
THE TELEGRAPH - Derek Angus (BCHS '92), chair of critical care medicine and HPM distinguished professor, says hard conversations about who should be prioritized will be needed both within and between countries. It might be decided that frontline workers should be at the head of the queue, but you could say that minorities who have a disproportionate burden of the disease should have a chance. You must be transparent about your principles of fair...
NEW YORK TIMES - “We really can’t isolate the impact of school closures from other interventions,” said HPM’s Julie Donohue. “I do worry that these large estimates of the effect of school closures will lead people to give up because it is going to be challenging to open schools. I do worry that some districts will look at these numbers and say, well, it’s just too hard and it’s not safe to reopen.”
AP NEWS - HPM’s Derek Angus, UPMC’s critical care chief, is using an innovative study using artificial intelligence to help pick treatments. Forty regional hospitals joined more from the United Kingdom to randomly assign patients to one of dozens of possible treatments, adapting treatments based on the results. If a drug looks like a winner, the computer assigns more people to get it. The system “learns on the fly.
WTAE NEWS - In the absence of a vaccine, said HPM Chair Mark Roberts, at least 60% of the population must contract and recover from the virus. But 1 percent of COVID-19 cases are fatal. “That’s a huge number of deaths in Allegheny County to achieve herd immunity.” If we continue without vaccine, eventually we will achieve herd immunity, but it comes at a cost of lives lost and overwhelmed hospitals.
WTAE - Officials said the new cases ranged in age from four months to 97 years old, with a median age of 31 years old. HPM's Mark Roberts, director of the Public Health Dynamics Laboratory, says he's concerned about this rise in cases, but at this point doesn't fear a larger spike in cases like other states. "It's not the virus. It's our response to the virus that causes the spike. It's not the virus getting stronger or weaker, it's how we respo...
After 49 years and three months, Lynette Clark retired on March 31. As a life member of the Pittsburgh Athletic Association, Lynette has worked extensively with the African American Alumni Council (AAAC) and other campus and community organizations. Read more about Lynette and our other recent retirees.
PITTWIRE - The new Healthcare Advisory Group, headed by Anantha Shekhar, new senior vice chancellor for the health sciences and dean of Pitt Med, will monitor the health status of the campus and ensure compliance with legal regulations. Members, including HPM’s Mark Roberts, EPI’s Anne Newman, EOH’s Sally Wenzel, will develop recommendations for the Pitt community.
NEWMAN TIMES-HERALD – As COVID-19 ravages the U.S., many of the nation’s 15,600 nursing homes are among the most dangerous places to be. Interim Dean Everette James says fixing the situation would require federal law changes that support a “functioning long-term care insurance market,” so more Americans can afford the type of care the wish for in their final years.