Yuanpu Peter Di, PhD, MBA

Associate Professor, Environmental and Occupational Health


Public Health Building 4139, 130 De Soto Street 15261
R-znvy: crgreqv@cvgg.rqh
Primary Phone: 967-179-3263
Secondary Phone: 967-179-4012
Fax: 967-179-4816
Web site:

Personal Statement

The purpose of my laboratory’s research is to investigate the effects of environmental exposure on the host. We are particularly interested in infection and immunity on the lung and its associated pathophysiological response during injury, repair, and regeneration. The primary focus of my current research is the cellular and molecular actions of exposures to toxic chemicals and microorganisms that underlie the pathogenesis of chronic human diseases.


  1. Lung epithelial cell phenotype, differentiation, and function upon exposure:

My laboratory provided influential identification and characterization of a novel lung epithelial cell specific, secretory protein SPLUNC1 and its roles in pulmonary diseases. The SPLUNC1-associated research has been supported by two consecutive R01 grants since 2008 including the ongoing clinical ancillary study to investigate its association with exacerbation in severe asthma. We and others have demonstrated multiple functions of SPLUNC1, including host defense, anti-inflammatory effects, a surfactant-like property, and modulation of epithelial lining fluid volume. The expression of SPLUNC1 in lung is dynamic and reflects maturational, functional, and pathological changes of lung epithelium. We are very interested in elucidating mechanisms associated with epithelial cell-mediated tissue remodeling and regeneration after recurrent bacterial and viral infection-induced injury.


  1. Inflammation-associated tissue remodeling and lung tumorigenesis:

My laboratory developed and published an innovative exposure paradigm that demonstrated the synergistic effect of lung tumorigenesis (> 6 fold, p<0.0001) and higher frequency of lung tumors that harbor K-ras mutation by co-exposure of a cigarette smoke carcinogen NNK and an inflammation eliciting agent from bacteria endotoxin LPS. We have found the inflammation-associated lung tumorigenesis is differentially regulated by genders and happens with higher frequency and incidence in the females than the males. Our ongoing research effort is to understand the mechanisms and further define the roles of inflammatory mediators in the regulation of the pathogenesis associated with lung tissue remodeling and carcinogenesis after recurrent infections. Our inflammation-associated cancer model demonstrated an immunosuppressive environment that promotes T-cell exhaustion and tumorigenesis. We have also used the valuable model to determine the checkpoint blockade-based immunotherapy and generated gene signature that provided high predictive value to anti-PD1 therapeutic response in lung cancer patients. Additionally, We have a vast interest in lung stem cell biology. My lab developed mouse and human primary epithelial cell cultures for both proximal tracheal-bronchial epithelial (TBE) and distal bronchiolar epithelial (DBE) cells as excellent tools for studying effects and mechanisms of progenitor cell renewal and environment exposure. Our results revealed that intrinsic phenotypic and genotypic changes in epithelial cells can be maintained, observed, and analyzed in an ALI cell culture system and that the DBE cells may reflect pathologic changes of lung tissue remodeling and adult lung stem cell regeneration.


  1. Development of novel antibiotics to overcome antimicrobial resistance (AMR):

Our effort in identifying the effects of antimicrobial milieu on host defense against respiratory infection resulted in the successful development of a next-generation peptide-based antibiotics (PAX) that demonstrate exciting and promising efficacy in overcoming multi-drug resistant (MDR) bacterial infection. New therapies for controlling MDR pathogen-induced respiratory infections are urgently needed because: (a) the mortality rate among infected individuals requiring hospitalization remains very high; and (b) overuse of antibiotics has resulted in continuing emergence of additional MDR strains with increased virulence. We have recently started two five-year R01 funding support from NIAID (as PI) and NIGMS (as Co-I with my assistant professor PI) to characterize the biological response involved in the disposition of novel antimicrobial agents, define pharmacokinetic information for the development of PAX therapy, and investigate the toxicological effects caused by therapeutic drugs. On an alternative approach in elucidating the antimicrobial resistant mechanisms associated with standard of care antibiotics and host microenvironment, we have developed novel biofilm assay to investigate bacterial adaption and evolution with analysis using whole genome sequencing (WGS) and bioinformatics. Our effort in combating AMR and developing PAX not only fills the void of lacking effective antibiotics against MDR infection but also provide a new functional model to investigate the host-pathogen interaction and determine the regenerative capacity of restoring lung epithelial cell function in preserving cell junctional integrity to protect lung from bacterial infection.



1986 | National Defense Medical Center | Medicine Certificate      

1995 | SUNY at Buffalo (Roswell Park Div.) | Biophysics Ph.D.              

1999 | University of California at Davis | Innovation & Technology Managment M.B.A.            


EOH 3210, Molecular Fundamentals

ARTSC 0130, First Experiences in Research

Selected Publications

Selected Publications Since 2011


F. Gally, Y.P. Di, S. K. Smith, M. N. Minor, Y. Liu, D. L Bratton, S. C. Frasch, N. M. Michels, S. R. Case and H.W. Chu. SPLUNC1 promotes lung innate defense against Mycoplasma pneumoniae infection in mice. American Journal of Pathology 178(5):2159-67. May, 2011. PMID:21514430


G. D. Leikauf, V. J. Concel,  P. Liu,  A. Berndt, A. S. Jang, K. Bein, K. A. Brant, M. Dietsch, H. Pope-Varsalona, R. A. Dopico, Jr., Y.P. Di, Q. Li,  L. J. Vuga, M. Medvedovic, N. Kaminski, M. You, D. Prows. Haplotype association mapping of survival during acute lung injury in mice implicates transforming growth factor beta signaling. American Journal of Respiratory and Critical Care Medicine 183(11):1499-509. Jun 1, 2011, Epub 2011 Feb 4, PMID:21297076


L. Lukinskiene, S. Reynolds, C. Steele, B. Stripp, G.Leikauf, J. Kolls, and Y.P. Di.  Antimicrobial activity of PLUNC protects against Pseudomonas aeruginosa infection. Journal of Immunology, 187(1):382-90. Jul 1, 2011, Epub 2011 Jun 1. PMID:21632717


N Vo, D Wang, G Sowa, W Witt, K Ngo, P Coelho, R Bedison, B Byer, R Studer, J Lee, Y.P. Di, and J Kang. Differential effects of nicotine and tobacco smoke condensate on human annulus fibrosus cell metabolism. Journal of Orthopaedic Research 2011 Mar 29. doi: 10.1002/jor.21417. [Epub ahead of print] PMID:21448984


Y.P. Di. Functional roles of SPLUNC1 in innate immune response against gram-negative bacteria. Biochemical Society Transactions 2011 Aug 1;39(4):1051-5 PMID:21787346


P. Keohavong, B. Kahkonon, E. Kinchington, J. Yin, X. Liu, J. Jin, J. M. Siegfried and Y.P. Di. K-ras mutations in lung tumors from NNK-treated mice with lipopolysaccharide-elicited lung inflammation. Anticancer Research 2011 Sep;31(9):2877-82) PMID:21868532


T. Richards,  C. Park, Y. Chen, K. F. Gibson, Y. P. Di, A. Pardo, S. Watkins5,  M. Selman, J. Pilewski, F. Sciurba, N. Kaminski, Y. Zhang. Allele Specific Transactivation of Matrix Metalloproteinase 7 by FoxA2 and Correlation with Plasma Levels in Idiopathic Pulmonary Fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology 2012 Apr; 302(8):L746-54. Epub 2012 Jan 20. PMID: 22268124


S. Tao, L. Zhu, P. Lee, W. Lee, , K. Knox, J. Chen, Y. P. Di and Yin Chen. Negative control of TLR3 signaling by TICAM1 downregulation. American Journal of Respiratory Cell and Molecular Biology 2012 May; 46(5):660-7. Epub 2011 Dec 28. PMID: 22205631


G.D. Leikauf, H. Pope-Varsalona, V.J. Concel, P. Liu, K. Bein, A. Berndt, T.M. Martin, K. Ganguly, A.S. Jang, K.A. Brant, R.A. Dopico Jr, S. Upadhyay, Y. P. Di, Q. Li, Z. Hu, L.J. Vuga, M. Medvedovic, N. Kaminski, M. You, D.C. Alexander, J.E. McDunn, D.R. Prows, D.L. Knoell, J.P. Fabisiak. Integrative assessment of chlorine-Induced acute lung injury in mice  American Journal of Respiratory Cell and Molecular Biology 2012 Mar 23. [Epub ahead of print] PMID: 22447970


J.V. Thaikoottathil, R.J. Martin, Y. P. Di, M. Minor, S. Case, B. Zhang, G. Zhang, H. Huang, H.W. Chu. SPLUNC1 Deficiency Enhances Airway Eosinophilic Inflammation in Mice. American Journal of Respiratory Cell and Molecular Biology 2012 Apr 12. [Epub ahead of print] PMID: 22499853


R. Birru, B, Kahkonon, and Y. P. Di. Chronic Inflammation in the Pathogenesis of COPD and Lung Cancer. Proceedings of the American Thoracic Society 2012 May; 9(2):81. PMID: 22550252


Y. P. Di, J. Zhao, and R. Harper. Cigarette smoke induces MUC5AC expression through the activation of Sp1. Journal of Biological Chemistry 2012 Aug 10;287(33):27948-58. Epub 2012 Jun 14. PMID: 22700966


Y. Liu and Y. P. Di. Effects of second hand smoke on airway secretion and mucociliary clearance. Frontiers in Physiology 3:342. doi: 10.3389/fphys.2012.00342, PMID: 22973232 IF=4.13


R. Birru, and Y. P. Di. Pathogenic mechanism of lung diseases associated with cigarette smoke induced inflammation. Frontiers in Physiology 3:348. doi: 10.3389/fphys.2012.00348, PMID: 22973236


S. Sayeed, L. Nistico, C. St Croix, and Y. P. Di. Multifunctional role of human SPLUNC1 in Pseudomonas aeruginosa infection. Infection And Immunity 2013 Jan; 81(1):285-91. doi: 10.1128/IAI.00500-12. Epub 2012 Nov 6.PMID: 23132494


Y. Liu, J. A. Bartlett, M. E. Di, J. M. Bomberger, Y. R. Chan, L. Gakhar, R. K. Mallampalli, P. B. McCray, Jr., and Y. P. Di. SPLUNC1/BPIFA1 contributes to pulmonary host defense against Klebsiella pneumoniae respiratory infection. American Journal of Pathology 2013 May;182(5):1519-31. doi: 10.1016/j.ajpath.2013.01.050..PMID: 23499554


G.D. Leikauf, V.J. Concel, K. Bein, P. Liu, A. Berndt, T.M. Martin, K. Ganguly, A.S. Jang, K.A. Brant, R.A. Dopico Jr, S. Upadhyay, C.L. Cario, Y. P. Di, L.J. Vuga, E. Kostem, E. Eskin, M. You, N. Kaminski, D..R Prows, D.L. Knoell, J.P. Fabisiak. Functional Genomic Assessment of Phosgene-induced Acute Lung Injury in Mice. American Journal of Respiratory Cell and Molecular Biology 2013 Apr 5. [Epub ahead of print] PMID: 23590305


Volonte D, Liu Z, Musille PM, Stoppani E, Wakabayashi N, Y. P. Di, Lisanti MP, Kensler TW, Galbiati F. Inhibition of nuclear factor-erythroid 2-related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence. Molecular Biology of the Cell 2013 Jun;24(12):1852-62. doi: 10.1091/mbc.E12-09-0666. Epub 2013 May 1. PMID: 23637463


Y. P. Di, A. V. Tkach, N. Yanamala, S. Stanley, S Gao, M. R. Shurin, E. R Kisin, V. E. Kagan, A. Shvedova. Dual Acute Pro-Inflammatory and Anti-Fibrotic Pulmonary Effects of SPLUNC1 After Exposure to Carbon Nanotubes. American Journal of Respiratory Cell and Molecular Biology 2013 May 30. [Epub ahead of print] PMID: 23721177


Y. Liu, M. E. Di, H.W. Chu, X. Liu, L. Wang, S. Wenzel, and Y. P. Di. Increased susceptibility to pulmonary Pseudomonas infection in Splunc1 knockout mice. Journal of Immunology 2013 Oct 15;191(8):4259-4268. Epub 2013 Sep 18.PMID: 24048904


Y.P. Di. Assessment of pathological and physiological changes in mouse lung through bronchoalveolar lavage. Methods in Molecular Biology 2014;1105:33-42. doi: 10.1007/978-1-62703-739-6_3. PMID: 24623217


Y. Zhang, R Birru, and Y.P. Di. Analysis of clinical and biological samples using microsphere based multiplexing Luminex system. Methods in Molecular Biology 2014;1105:43-57. doi: 10.1007/978-1-62703-739-6_4. PMID: 24623218


L Zhu, Y.P. Di, R Wu, KE Pinkerton, Y Chen. Repression of CC16 by cigarette smoke (CS) exposure. PLOS One 2015 Jan 30;10(1):e0116159. doi: 10.1371/journal.pone. 0116159. eCollection 2015. PMID: 25635997


B Lee, KM Robinson, KJ McHugh, EV Scheller, S Mandalapu, C Chen, Y.P. Di, ME Clay, RI Enelow, PJ Dubin, JF Alcorn. Influenza-induced Type I Interferon Enhances Susceptibility to Gram-negative and Gram-positive Bacterial Pneumonia in Mice. American Journal of Physiology. Lung Cellular and Molecular Physiology 2015 May 22;ajplung.00338.2014. PMID:26001778. doi:10.1152/ajplung.00338.2014.


A. Di Grazia, F. Cappiello, H. Cohen, B Casciaro, V. Luca, A. Pini, Y.P. Di, Shai, and M.Mangoni. D-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions. Amino Acids 2015 Dec;47(12):2505-19. doi: 10.1007/s00726-015-2041-y. PMID: 26162435


D. G. Phinney, M. Di Giuseppe, J. Njah, E. Sala, S. Shiva, C. M. St Croix, D. B. Stolz, S. C. Watkins, Y.P. Di, G. D. Leikauf, J. Kolls, D. W. Riches, G. Deiuliis, N. Kaminski, S. V Boregowda, D. H. McKenna, and L. A. Ortiz. Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle micro RNAs. Nature Communication 2015 Oct 7;6:8472. doi: 10.1038/ncomms9472. PMID: 26442449


E. Travanty, B. Zhou, H. Zhang, Y.P. Di, J. Alcorn, D. Wentworh, R. Mason, and J. Wang. Differential susceptibility of human lung primary cells to H1N1 influenza viruses. Journal of Virology 2015 Dec;89(23):11935-44. doi: 10.1128/JVI.01792-15. Epub 2015 Sep 16. PMID: 26378172


W.G Walton, S Ahmad, MS Little, CS Kim, J Tyrrell, Q Lin, Y.P. Di, R Tarran, MR Redinbo. Structural features essential to the antimicrobial functions of human SPLUNC1. Biochemistry 2016 May 31;55(21):2979-91. doi: 10.1021/acs.biochem.6b00271. Epub 2016 May 17. PMID: 27145151


F. Cappiello, A. Di Grazia, L. Segev-Zarko, S. Scali, L. Ferrera, L. Galietta, A. Pini, Y. Shai, Y. P. Di, and M. Mangoni. Esculentin-1a-derived peptides promote clearance of P. aeruginosa internalized in cystic fibrosis bronchial cells as well as lung cells migration: Biochemical properties and a plausible mode of action. Antimicrobial Agents and Chemotherapy 2016; 60(12):7252-7262. PMID: 27671059


T. Wu, J. Huang, P.J. Moore, M.R. Little, W.G. Walton, R.C. Fellner, N. E. Alexis, Y.P. Di, M.R. Redinbo, S.L. Tilley and R. Tarran. Identification of BPIFA1 as an epithelium-derived smooth muscle relaxing factor. Nature Communication 8, Published online: 06 February 2017 doi:10.1038/ncomms14118. PMID: 28165446


Y Chen, M. M. Vasquez, L. Zhu, R. E. Lizarraga, M. Krutzsch, J. Einspahr, D. S. Alberts, Y.P. Di, F. D. Martinez, and S. Guerra. Effects of retinoids on augmentation of club cell secretory protein. American Journal of Respiratory and Critical Care Medicine 2017 Feb 23. doi: 10.1164/rccm.201608-1611LE. PMID: 28231434


B. Deslouches and Y.P. Di. Antimicrobial peptides with selective antitumor mechanisms: prospect for anticancer applications. Oncotarget 2017 Mar 31. doi: 10.18632/oncotarget. 16743. PMID: 28422728, PMCID: PMC5542299


C. Chen, M. Mangoni, and Y.P. Di. In vivo therapeutic efficacy of frog skin-derived peptides against Pseudomonas aeruginosa-induced pulmonary infection. Scientific Reports 2017 Aug 17;7(1):8548. doi: 10.1038/s41598-017-08361-8. PMID: 28819175, PMCID: PMC5561116


K. Ngo, P. Pohl, D. Wang, A. Leme, J. Lee, Y.P. Di, P. Roughley, P.D. Robbins, L. Niedernhofer, G. Sowa, J. Kang, S. Shapiro and N.V. Vo. ADAMTS5 Deficiency Protects Mice From Chronic Tobacco Smoking-induced Intervertebral Disc Degeneration. Spine (Phila Pa 1976). 2017 Oct 15;42(20):1521-1528. doi: 10.1097/BRS.0000000000002258. PMID: 28570296, PMCID: PMC5633483


B. Deslouches and Y.P. Di. Antimicrobial Peptides: A Potential Therapeutic Option for Surgical Site Infections. Clinics in Surgery 2017 Nov 2;1740: 1-4. NIHMS981044


E. Caves, R. Butch, S. Cook, L. Wasil, C. Chen, Y.P. Di, N. Lee, and K. Shair. Latent Membrane Protein 1 is a novel determinant of Epstein-Barr virus genome persistence and reactivation. mSphere 2017 Nov 8: 2 (6): e00453-17. PMID: 29134204, PMCID: PMC5677982


D. Volonte, A. Vyas, C. Chen, S. Dacic, L. Stabile, B. Kurland, S. Abberbock, T. Burns, J. Herman, Y.P. Di and F. Galbiati. Caveolin-1 promotes the tumor suppressor properties of oncogene-induced cellular senescence. Journal of Biological Chemistry 2018 Feb 2; 293(5):1794-1809. doi: 10.1074/jbc.M117.815902. Epub 2017 Dec 15.PMID: 29247004, PMCID: PMC5798308


C. Chen, B. Deslouches, R. Montelaro and Y.P. Di. Enhanced efficacy of the engineered antimicrobial peptide WLBU2 via direct airway delivery in a murine model of P. aeruginosa pneumonia. Clinical Microbiology and Infection  2018 May; 24(5):547.e1-547.e8. NIHMSID: NIHMS903948. PMID: 28882728, PMCID: PMC5835169


C. Chen, X Zhang, Q. Lin, N. Remlinger, T. Gilbert and Y.P. Di. Urinary bladder matrix protects host in a murine model of bacterial-induced lung infection. Tissue Engineering, Part A 2018 Jul 18; https://doi.org/10.1089/ten.TEA.2018.0080, DOI: 10.1089/ten.TEA.2018. 0080 PMID: 30019635


Z. Yu, B. Deslouches, W. G. Walton, M. R. Redinbo, and Y.P. Di. Enhanced biofilm prevention activity of a SPLUNC1-derived antimicrobial peptide against Staphylococcus aureus. PLOS ONE 2018 Sep 14; 13(9):e0203621. doi: 10.1371/journal.pone.0203621. eCollection 2018 PMID: 30216370, PMCID: PMC6138395


Q. Lin, B. Deslouches, RC. Montelaro and Y.P. Di. Prevention of ESKAPE pathogen biofilm formation by antimicrobial peptides WLBU2 and LL37. International Journal of Antimicrobial Agents 2018 Nov; 52(5):667-672. doi: 10.1016/j.ijantimicag.2018.04.019. PMID: 29753132, PMCID: PMC6230315


A. Kumagai, F. G. Dupuy, Z. Arsov, Y. Elhady, D. Moody, R. K. Ernst, B. Deslouches, R. C. Montelaro, Y. P. Di, and S. Tristram-Nagle. Elastic behavior of model membranes with antimicrobial peptides depends on lipid specificity and D-enantiomers. Soft Matter 2019 Jan 31; DOI: 10.1039/c8sm02180e, PMID: 30702120


S. Jiang, B. Deslouches, C. Chen, M. E. Di, and Y. P. Di. Antibacterial Properties and Efficacy of a Novel SPLUNC1-Derived Antimicrobial Peptide, α4-Short, in a Murine Model of Respiratory Infection. mBio 2019 Apr 9;10(2). pii: e00226-19. doi: 10.1128/mBio.00226-19. DOI: 10.1128/mBio.00226-19. PMID: 30967458


N. Schaefer, M. A. X. Li, Seibold, N. N. Jarjour, L. C. Denlinger, M. Castro, A. M. Coverstone, W. G. Teague, J. Boomer, E. R. Bleecker, D. A. Meyers, J. Fahy, B. R. Phillips, D. T. Mauger, A. Dakhama, S. Gellatly, R. Berman, Y. P. Di*, S. E. Wenzel*, and H. W. Chu* (*co-corresponding authors). The effect of SPLUNC1 genetic variation on its expression and function in asthmatic airway epithelial cells. JCI Insight 2019 Apr 18;4(8). pii: 127237. doi: 10.1172/jci.insight.127237. eCollection 2019 Apr 18. PMID: 30996135


B. Casciaro, I. d'Angelo, X. Zhang, M. Loffredo, G. Conte, F. Cappiello, F. Quaglia, Fabiana; Y. P. Di, F. Ungaro, and M. Mangoni. Poly(lactide-co-glycolide) nanoparticles for prolonged therapeutic efficacy of esculentin-1a-derived antimicrobial peptides against Pseudomonas aeruginosa lung infection: in vitro and in vivo studies. Biomacromolecules 2019 Apr 23. doi: 10.1021/acs.biomac.8b01829. PMID: 31013061


B. Casciaro, Q. Lin, S. Afonin, M. R. Loffredo, V. de Turris, V. Middel, A. S. Ulrich, Y. P Di, and M. L. Mangoni. Inhibition of Pseudomonas aeruginosa biofilm formation and expression of virulence genes by selective epimerization in the peptide Esculentin‐1a(1‐21)NH2. The FEBS Journal 2019 May 30. doi: 10.1111/febs.14940. PMID: 31144441


Z. Li, M. Zeng, Y. Deng, J. Zhao, X. Zhou, J.B. Trudeau, E. Goldschmidt, J.A. Moore, H. Chu, W. Zhang, S. Yin, Z. Liu, Y. P. Di, S.E. Lee, S.E. Wenzel. Nasal polyps 15-lipoxygenase 1 promotes CCL26/Eotaxin3 expression through ERK activation. Journal of Allergy and Clinical Immunology 2019 Jul 10. pii: S0091-6749(19)30905-4. doi: 10.1016/j.jaci.2019. 06.037. [Epub ahead of print] PMID: 31301373


B. Mashbat, E. Bellos, S. Hodeib, F Bidmos, R. S. Thwaites, Y. Lu, V. Wright, J. Herberg, D. S. Klobassa, W. Zenz, T. Hansel, S. Nadel, P. R. Langford, L. J. Schlapbach, M. Li, M. Redinbo, Y. P. Di, M. Levin and V. Sancho-Shimizu. A rare mutation in SPLUNC1 underlies meningococcal disease affecting bacterial adherence and invasion. Clinical Infectious Diseases (In Press) doi: 10.1093/cid/ciz600



Book Chapters


Y. Zhang, R Birru, and Y.P. Di. Analysis of clinical and biological samples using microsphere based multiplexing Luminex system. Methods Mol Biol. 2014;1105:43-57. doi: 10.1007/978-1-62703-739-6_4. PMID: 24623218


Y.P. Di. Assessment of pathological and physiological changes in mouse lung through bronchoalveolar lavage. Methods Mol Biol. 2014;1105:33-42. doi: 10.1007/978-1-62703-739-6_3. PMID: 24623217


M. Mangoni, F. Cappiello, B. Casciaro, V. Luca, C. Chen, Q. Lin and Y.P. Di. Development and preclinical testing of a novel antimicrobial peptide to treat Pseudomonas aeruginosa-induced lung infections. FFC Proceedings 2016


Maria Luisa Mangoni, Floriana Cappiello, Bruno Casciaro, Chen Chen, Debarun Dutta, Alison McDermott, Mark Dp. Willcox, Y.P. Di. How to control Pseudomonas aeruginosa-induced pneumonia and keratitis? A lesson from the amphibian skin-derived peptide Esculentin(1-21) and its diastereomer. https://doi.org/10.17952/35EPS.2018.228


Marissa E. Di, Dandan Yang, and Y.P. Di. Using bronchoalveolar lavage to evaluate changes in pulmonary diseases. Molecular Toxicology Protocols, Third Edition (In Press)


Qiao Lin and Y.P. Di. Determination and quantification of bacterial virulent gene expression using quantitative real time PCR. Molecular Toxicology Protocols, Third Edition (In Press)


Yingze Zhang, Xiaoyun Li, and Y.P. Di. Fast and efficient measurement of clinical and biological samples using immunoassay-based multiplexing systems. Molecular Toxicology Protocols, Third Edition (In Press)


Chia-Hsin Liu and Y.P. Di. Analysis of RNA Sequencing Data using CLC Genomics Workbench. Molecular Toxicology Protocols, Third Edition (In Press)

Yuanpu Peter Di