Mary G Krauland, PhD

I work with the modeling and simulation platform FRED (Framework for Reconstructing Epidemiological Dynamics), developed by the Public Health Dynamics Laboratory at Pitt Public Health. FRED is an agent-based modeling system that has been used to simulate diverse scenarios such as infectious disease outbreaks, impact of mitigation strategies, and responses to emergency situations. I have contributed to a number of FRED projects, including the addition of long-term demographic dynamics, travel simulation, impact of behavior on vaccination dynamics, population-level income changes over time, development of behavioral risk models of alcohol-related problems and modeling the opioid epidemic. I have also worked on the development of a model to estimate impact of interventions on deficits in health care resources and to a model that explored the relationship of social determinants to cardiovascular disease risk. I am interested in adding more complex disease models to FRED.

2008 | University of Pittsburgh, Pittsburgh, PA | PhD

Guest Lecturer, PUBHLT 2016

Guest Lecturer, BCHS 2990

Guest Lecturer, EPIDEM/IDM 2161

1.        Brett T, Ajelli M, Liu QH, Krauland MG, Grefenstette JJ, van Panhuis WG, Vespignani A, Drake JM, Rohani P. Detecting critical slowing down in high-dimensional epidemiological systems. PLoS Comput Biol. 2020 Mar 9;16(3):e1007679. doi: 10.1371/journal.pcbi.1007679. eCollection 2020 Mar.

2.         Sinclair DR, Grefenstette JJ, Krauland MG, Galloway DD, Frankeny RJ, Travis C, Burke DS, Roberts MS. Forecasted Size of Measles Outbreaks Associated With Vaccination Exemptions for Schoolchildren. JAMA Netw Open. 2019 Aug 2;2(8):e199768. doi: 10.1001/jamanetworkopen.2019.9768

3.         Guclu H, Kumar S, Galloway D, Krauland M, Sood R, Bocour A, Hershey TB, van Nostrand E, Potter M. An Agent-Based Model for Addressing the Impact of a Disaster on Access to Primary Care Services. Disaster Med Public Health Prep. 2016 Jun; 10(3):386-93. PMID: 27075561.

4.         Mustapha MM, Marsh JW, Krauland MG, Fernandez JO, de Lemos AP, Dunning Hotopp JC, Wang X, Mayer LW, Lawrence JG, Hiller NL, Harrison LH. Genomic Investigation Reveals Highly Conserved, Mosaic, Recombination Events Associated with Capsular Switching among Invasive Neisseria meningitidis Serogroup W Sequence Type (ST)-11 Strains. Genome Biol Evol. 2016 Jul 3;8(6):2065-75. PMID: 27289093.

5.         Mustapha MM, Marsh JW, Krauland MG, Fernandez JO, de Lemos AP, Dunning Hotopp JC, Wang X, Mayer LW, Lawrence JG, Hiller NL, Harrison LH. Genomic Epidemiology of Hypervirulent Serogroup W, ST-11 Neisseria meningitidis. EBioMedicine. 2015 Sep 8;2(10):1447-55. PMID: 26629539.

6.         Marsh JW, Krauland MG, Nelson JS, Schlackman JL, Brooks AM, Pasculle AW, Shutt KA, Doi Y, Querry AM, Muto CA, Harrison LH. Genomic Epidemiology of an Endoscope-Associated Outbreak of Klebsiella pneumoniae Carbapenemase (KPC)-Producing K. pneumoniae. PLoS One. 2015 Dec 4; 10(12):e0144310. PMID: 26637170.

7.         Barroso DE, Castiñeiras TM, Freitas FS, Marsh JW, Krauland MG, Tulenko MM, Fonseca ÉL, Vicente AC, Rebelo MC, Cerqueira EO, Xavier AC, Cardozo AP, da Silva SE, Harrison LH. Three outbreak-causing Neisseria meningitidis serogroup C clones, Brazil. Emerg Infect Dis. 2013 Nov; 19(11):1847-50. doi: 10.3201/13-0610. PMID: 24229563.

8.         Barroso DE, Castiñeiras TM, Cabral AC, Vicente AC, Rebelo MC, Cerqueira EO, Tulenko MM, Marsh JW, Krauland MG, Harrison LH. Neisseria meningitidis ST-11 clonal complex bearing capsule serogroups B, C, or W in Brazil. J Infect. 2013 Jan 12. doi:pii: S0163-4453(13)00006-6. 10.1016/j.jinf.2013.01.002. PMID: 23321151.

9.         Barroso DE, Castiñeiras TM, Rebelo MC, Tulenko MM, Marsh JW, Krauland MG, Harrison LH. Invasive Neisseria meningitidis Strain Expressing Capsular Polysaccharides W and Y in Brazil. J Clin Microbiol. 2013 Mar; 51(3):1059-60. doi: 10.1128/JCM.02787-12. Epub 2012 Dec 26. PMID: 23269739.

10.       Castiñeiras TM, Barroso DE, Marsh JW, Tulenko MM, Krauland MG, Rebelo MC, Harrison LH. Capsular Switching in Invasive Neisseria meningitidis, Brazil. Emerg Infect Dis. 2012 Aug; 18(8):1336-8. PMID: 22840713.

11.       Achtman M, Wain J, Weill FX, Nair S, Zhou Z, Sangal V, Krauland MG, Hale JL, Harbottle H, Uesbeck A, Dougan G, Harrison LH, Brisse S; S. Enterica MLST Study Group. Multilocus sequence typing as a replacement for serotyping in Salmonella enterica. PLoS Pathog. 2012; 8(6):e1002776. PMID: 22737074.8(6):e1002776. PMID: 22737074.

12.       Krauland MG, Dunning Hotopp JC, Riley DR, Daugherty SC, Marsh JW, Messonnier NE, Mayer LW, Tettelin H, Harrison LH. Whole Genome Sequencing to Investigate the Emergence of Clonal Complex 23 Neisseria meningitidis Serogroup Y Disease in the United States. PLoS One. 2012; 7(4): e35699. PMID: 22558202.

13.       Krauland M, Harrison L, Paterson D, Marsh J. Novel integron gene cassette arrays identified in a global collection of multi-drug resistant non-typhoidal Salmonella enterica. Current Microbiology. 2010 Mar; 60(3):217-23. PMID: 19921331

14.       Krauland MG, Marsh JW, Paterson DL, Harrison LH. Integron-mediated multidrug resistance in a global collection of nontyphoidal Salmonella enterica isolates. Emerging Infectious Diseases. 2009 Mar; 15(3):388-96. PMID: 19239750.