Jun Zhang of the Department of Biostatistics defends her dissertation on "Interpretable Analysis of Multivariate Functional Data".
The Joint Statistical Meetings, known simply as "JSM", is the largest gathering of statisticians held annually in North American. Faculty and student presenters from the Department of Biostatistics regularly participate giving invited talks, contributed talks, and poster presentations. Our students often receive top awards and participate in the affiliated career marketplace at the event.
Meetings of the Eastern North American Region of the International Biometric Society (a.k.a. "ENAR meetings") are held in late March or early April each year and reflect the broad interests of the Society, including both quantitative techniques and application areas. Faculty and student presenters from the Department of Biostatistics regularly participate giving invited talks, contributed talks, and poster presentations.
Translation of single-cell genomics into human health: methods and applications
Abstract: Recent technological breakthroughs have made it possible to measure gene expression at the single-cell level, thus allowing biologists and clinicians to better understand cellular heterogeneity and modify cell behavior through targeted molecular therapies. However, single-cell RNA sequencing protocols are complex. Even with the most sensitive platforms, the data are often noisy owing to a high frequency of dropout events, and the phenomenon of transcriptional bursting in which pulses of transcriptional activity are followed by inactive refractory periods. In this talk, I will present several statistical and machine learning methods that aim to tackle these challenges for a better understanding of cellular heterogeneity. I will illustrate our methods by showing results from ongoing collaborations on age-related macular degeneration and Alzheimer’s disease. With the growing interest in utilizing single-cell technologies in biomedical research, our methods will aid biomedical researchers to answer medically related questions and make exciting discoveries.
Last Updated On Tuesday, September 3, 2019 by Tang, Lu
Created On Monday, August 12, 2019
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