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Research and Practice News

Check out some highlights of research and practice under way at Pitt Public Health:

Nachega finds drug-resistant TB cured with new approaches in conflict-affected region 

Nachega finds drug-resistant TB cured with new approaches in conflict-affected region

INFECTION CONTROL TODAY - A high proportion of multidrug-resistant tuberculosis cases can be cured in conflict-affected communities with molecular diagnostics, shorter treatment periods, and socioeconomic incentives, according to the results of a large, long-term study in the Democratic Republic of... (02/19/2019)

Scientists uncover dual-layered scaffolding of cellular nuclei (video) 

Scientists uncover dual-layered scaffolding of cellular nuclei (video)

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES  - Using super-sensitive microscopic imaging, a team of scientists led by HuGen's Quasar Padiath has made a fundamental biological discovery that explains the structure of the nuclear envelope and gives tantalizing clues as to how cells squish throug... (02/19/2019)

Catov among scientists researching heart disease link to pre-eclampsia 

Catov among scientists researching heart disease link to pre-eclampsia

PITTSBURGH COURIER - While her baby is still a toddler, a woman who had preeclampsia during her pregnancy might already be on the path to heart disease and not getting the care she needs. Perinatal epidemiologistJanet Catov is among those researchers examining what pregnancy-related signals identif... (02/14/2019)

Rosano links depressive symptoms in type 1 diabetes to extended hyperglycemia, brain lesions 

Rosano links depressive symptoms in type 1 diabetes to extended hyperglycemia, brain lesions

HELIO - Middle-aged adults with type 1 diabetes are more likely to experience depressive symptoms than those without, and extended hyperglycemia and more white matter hyperintensities in the brain may play a role in this difference, according to findings published in Diabetic Medicine by EPI's Cate... (02/13/2019)

Hartman among researchers trying to prevent virus more dangerous than Zika (video) 

Hartman among researchers trying to prevent virus more dangerous than Zika (video)

WPXI - Pitt researchers are looking to lessons learned about Zika when preparing for the possibility of Rift Valley Fever virus, noting that it's important to develop therapies and vaccines now. "We saw the ffects of Zika when it got into a larger population and so our work highlights the need to r... (02/11/2019)

Marques finds prior dengue infection protects against Zika 

Marques finds prior dengue infection protects against Zika

The higher a person's immunity to dengue virus, the lower their risk of Zika infection, an international team of scientists reported in the journal Science. The study also provides evidence that Brazil's Zika epidemic has largely petered out because enough people acquired immunity to reduce the eff... (02/11/2019)

Global Health at Home: Leff on Products of Pittsburgh podcast 

Global Health at Home: Leff on Products of Pittsburgh podcast

PRODUCTS OF PITTSBURGH - In 2013, Mara Leff (BCHS '16), now director of innovation at the Jewish Healthcare Foundation, moved from Washington, D.C., back to her hometown of Pittsburgh to study global health at Pitt Public Health. Her research took her across the world, although after graduating, Le... (02/11/2019)

Marsh, Buchanich, multiple alums publish first study of workers involved in aerospace materials manufacturing 

Marsh, Buchanich, multiple alums publish first study of workers involved in aerospace materials manufacturing

AMERICAN JOURNAL OF INDUSTRIAL MEDICINE - This is the first ever epidemiological study of workers involved in aerospace materials manufacturing. Authored by BIOST's Gary Marsh and Jeanine Buchanich and featuring work from Jessica Graves (BIOST '18, EPID '22), Yimeng (Alice) Lu (BIOST '17), and Sara... (02/11/2019)

Hernandez's research adds to pharmaceutical industry's growing pressure over high price of drugs 

Hernandez's research adds to pharmaceutical industry's growing pressure over high price of drugs

FOX NEWS - "It's not about innovation, it's about inflation in existing products," explains Inmaculada Hernandez (HPM '16). "They are the same companies that operate in other countries and they don't show this behavior and that's because in other countries they are lucky to have this regulatory env... (01/24/2019)

Garcia-Bates says timing of immunotherapy crucial to outcomes 

Garcia-Bates says timing of immunotherapy crucial to outcomes

MEDICAL RESEARCH - "HIV infection is a manageable disease with the advent and availability of combination antiretroviral therapy (ART). But, when ART is interrupted, the virus quickly rebounds to high levels and again targets the immune system. Therefore, new immunotherapeutic treatments are sought... (01/14/2019)

Hernandez's research says prescription drug costs driven by manufacturer price hikes, not innovation 

Hernandez's research says prescription drug costs driven by manufacturer price hikes, not innovation

WESA - The skyrocketing cost of many prescription drugs in the U.S. can be blamed primarily on price increases, not expensive new therapies or improvements in existing medications as drug companies frequently claim, says a new study published in Health Affairs by Inmaculada Hernandez (HPM '16).  (01/10/2019)

Hartman Researches Virus Even More Dangerous than Zika to Pregnant Women 

Hartman Researches Virus Even More Dangerous than Zika to Pregnant Women

THE NEW YORK TIMES - The mosquito-borne virus that causes Rift Valley fever may severely injure human fetuses if contracted by mothers during pregnancy, according to new research by IDM's Amy Hartman. "Zika caught everybody by surprise," said Hartman. "If doctors had known about Zika's birth effect... (01/09/2019)

Breastfeeding linked to less belly fat and smaller waist size 

Breastfeeding linked to less belly fat and smaller waist size

MEDICALRESEARCH.COM  - Work by Gabrielle Snyder (EPI '15) tests the association between breastfeeding duration and maternal waist circumference while controlling for race, socioeconomic status, and behavioral factors like better diet and more physical activity. The study found that women who breast... (01/04/2019)

Maseru co-writes Birth Equity Consensus Statement 

Maseru co-writes Birth Equity Consensus Statement

MARCH OF DIMES - BCHS's Noble Maseru co-authored "Birth Equity for Moms and Babies Concensus Statement" to advance social determinants pathways for research, policy, and practice. Among the recommendations: improve maternal death surveillance, expand research, engage in health system reform, empowe... (01/02/2019)

To reduce falls and fracture risk, improve sleep quality and length, Cauley says 

To reduce falls and fracture risk, improve sleep quality and length, Cauley says

PT PRODUCTS - "Even though falls are caused by a number of factors, our paper focuses on a novel risk factor: sleep. Results suggest that interventions aimed at improving sleep may reduce the risk of falls." says EPI's Jane Cauley.  (01/02/2019)

Study by Catov and colleagues finds breast-feeding tied to smaller waist size in mother 

Study by Catov and colleagues finds breast-feeding tied to smaller waist size in mother

NEW YORK TIMES - Breast-feeding for longer than six months may lead to a smaller waist size for the mother. “There are three wins here,” said EPI's Janet Catov. “There are short-term benefits for the mother — weight after pregnancy is something women care about. And there are long-term benefits for... (12/19/2018)

Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions 

Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions

JOURNAL OF VIROLOGY - Using samples from participants in the Multicenter AIDS Cohort study, Garcia-Bates, Palma, Shen, Gambotto, Macatangay, Ferris, Rinaldo, and Mailliard showed that PD-1 activation plays a positive role in initiating the primary T cell response. But later blocking of that pathway... (12/13/2018)

Talbott interviewed on new study linking air pollution and emergency room visits 

Talbott interviewed on new study linking air pollution and emergency room visits

THE ALLEGHENY FRONT - A new study finds that primary pollutants were linked with emergency room visits for cardiovascular and respiratory diseases. EPI's Evelyn Talbott says that the study incorporates data from 48 air monitors in the greater Pittsburgh region, and data from the area’s major health... (12/11/2018)

Windber the latest chosen to join WalkWorks network 

Windber the latest chosen to join WalkWorks network

THE TRIBUNE-DEMOCRAT - Steps are being taken to add a state-promoted walking route through Windber Recreation Park, as part of an effort to build healthier communities across PA. Windber and two other western PA communities were chosen to join the WalkWorks network – created by the Department of He... (12/11/2018)

Schulz research on life after bereavement is highlighted in 'Starts at 60' 

Schulz research on life after bereavement is highlighted in 'Starts at 60'

STARTS AT 60 - EPI and BCHS's Richard Schulz led a 2008 study on life after bereavement and found that 10 to 15% of carers would experience chronic depression after the death of the person they cared for. Interestingly, this percentage doubled for carers of people affected by dementia. The reason f... (12/11/2018)

Research Videos

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Scientists uncover dual-layered scaffolding of cellular nuclei (video) 

Scientists uncover dual-layered scaffolding of cellular nuclei (video)

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES  - Using super-sensitive microscopic imaging, a team of scientists led by HuGen's Quasar Padiath has made a fundamental biological discovery that explains the structure of the nuclear envelope and gives tantalizing clues as to how cells squish throug... (02/19/2019)
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Hartman among researchers trying to prevent virus more dangerous than Zika (video) 

Hartman among researchers trying to prevent virus more dangerous than Zika (video)

WPXI - Pitt researchers are looking to lessons learned about Zika when preparing for the possibility of Rift Valley Fever virus, noting that it's important to develop therapies and vaccines now. "We saw the ffects of Zika when it got into a larger population and so our work highlights the need to r... (02/11/2019)
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Hernandez's research adds to pharmaceutical industry's growing pressure over high price of drugs 

Hernandez's research adds to pharmaceutical industry's growing pressure over high price of drugs

FOX NEWS - "It's not about innovation, it's about inflation in existing products," explains Inmaculada Hernandez (HPM '16). "They are the same companies that operate in other countries and they don't show this behavior and that's because in other countries they are lucky to have this regulatory env... (01/24/2019)
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BCHS team tries new technique to share research with LGBTQ youth (video) 

BCHS team tries new technique to share research with LGBTQ youth (video)

Post-doctoral researcher Robert Coulter (BCHS '17), BCHS's Jessica Burke, and Sara Baumann (BCHS '19) tried using a video approach to share highlights of Coulter's recent research on how welcoming school environments reduce drinking among both LGBT+ -identified students and their heterosexual count... (11/24/2018)
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Burke updates Pitt Public Health community on state of the opioid epidemic (VIDEO) 

Burke updates Pitt Public Health community on state of the opioid epidemic (VIDEO)

Dean Donald S. Burke's third annual address to the school on the state of the nation's opioid overdose epidemic looks at one of the most pressing issues facing our region. Burke highlights his team's research recently published in  Science  ( Changing dynamics of the drug overdose epidemic in t... (10/04/2018)
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Newman and colleagues' new study uses local participants to look at aspirin use in older adults (video) 

Newman and colleagues' new study uses local participants to look at aspirin use in older adults (video)

WPXI - TV - We've long heard that an aspirin a day can help lower the risk of heart disease. A new study using participants from Pittsburgh suggests that isn't always the case. The study looked at 19,000 people worldwide, including 178 people from Pittsburgh. "People who took aspirin and people who... (09/19/2018)
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