IDM Department News

Zika and travel: Marques tells you what you need to know

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THE NEW YORK TIMES - The virus has been out of the headlines, but that doesn't mean it is gone. The World Health Organization just updated guideines for travelling to the Zika zone. "Summer in the north is winter in the south and vice versa, so you have to consider that," said IDM's Ernesto Marques. The virus is still circulating, but it's less prevalent in colder months than in the summer.   

The Zika virus is still a threat. Here's what Marques, other experts know

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THE NEW YORK TIMES - Remember Zika? With measles and Ebola grabbing headlines, it is easy to forget the health panic of 2016, when Zika was linked to severe birth defects in thousands of Brazilian newborns whose mothers were infected while pregnant, striking fear across the country and much of the Americas. "The next outbreak is not a matter of if, but when," said IDM's Ernesto Marques.   

Pitt Men's Study reflects on past, future of HIV fight

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THE PITT NEWS - When an outbreak of HIV hit the U.S. in the early 1980s, not much was known about the virus or how it spread. Scientists, researchers, and volunteers at Pitt have been working for almost four decades to try and change that. Reflecting on 40 years means celebrating successes, lamenting that the cure hasn't yet been found, and commending those original study participants that came forward in a tumultuous and uncertain time.   

40 Years of HIV Research: Grant Extends Lifetime of Pitt Men's Study

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UPMC NEWS - IDM Chair Charles Rinaldo recently received the news that a major study he directs to confidentially collect information on men living with HIV will be renewed into 2026 at nearly $4 million per year. The funding from the National Institutes of Health ensures that the Pitt Men's Study will survive into its fourth decade. But today, on HIV Long-Term Survivors Day, Rinaldo calls the remarkable milestone bittersweet.  

Cheyenne Annarumo awarded 2018-19 Bob Yee Scholarship

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Cheyenne Annarumo (IDM '20) was awarded a 2019 Bob Yee Public Health Scholarship. A native of Ellwood City, PA, Annarumo is pursuing an MPH with a concentration in infectious disease management, intervention, and community practice (MPH-MIC). She studied biology and was pre-med at Gannon University.   

Kelsey Simon awarded 2018-19 Bob Yee Scholarship

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Kelsey Simon (IDM '20) was awarded a 2019 Bob Yee Public Health Scholarship in recognition of academic excellence. A native of Buffalo, NY, Simon is pursuing an MPH in infectious disease pathogenesis, eradication, and laboratory practice (MPH-PEL). She holds an undergraduate biology degree from the University of Pittsburgh.   

Subramanian Thothathri awarded 2018-19 Bob Yee Scholarship

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Subramanian Thothathri (IDM '20) was awarded a 2019 Bob Yee Public Health Scholarship. A native of Chennai, India, Thothathri is pursuing an MS in infectious diseases and microbiology. He holds an undergraduate bioengineering degree from Sastra University.   

2019 Celebration of Student Awards

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On April 27, 2019, Pitt Public Health celebrated recent graduates with awards given upon the culmination of a degree program. Delta Omega's honor society inductees were announced and outstanding thesis/essay and dissertation awards were conferred. Outstanding Student Awards were also given at both the master's and doctoral level, as well as Dean's Service Awards.   

Nagy: 2019 Early Career Excellence Award

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Annie Nagy (IDM ’10) is the maternal and child health program administrator at the Allegheny County Health Department where she uses current public health science and evidence-based practices to manage the weC.A.R.E. and Healthy Families Allegheny programs. Nagy analyzes health information to assist in program implementation and establishes community relationships to promote and support the MCH Program’s strategic plan.  

Dean's Day 2019 IDM departmental award recipients

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Department of Infectious Diseases and Microbiology awards during our annual Dean's Day student research competition were given to Lindsay Summers (MPH '21), and Roberta Reis (PhD '19).  

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Recent IDM Publications

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Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions 

Contrasting roles of the PD-1 signaling pathway in dendritic cell-mediated induction and regulation of HIV-1-specific effector T cell functions

JOURNAL OF VIROLOGY - Using samples from participants in the Multicenter AIDS Cohort study, Garcia-Bates, Palma, Shen, Gambotto, Macatangay, Ferris, Rinaldo, and Mailliard showed that PD-1 activation plays a positive role in initiating the primary T cell response. But later blocking of that pathway... (12/13/2018)

Development of antibody biomarkers of long term and recent dengue virus infections 

Development of antibody biomarkers of long term and recent dengue virus infections

JOURNAL OF VIROLOGICAL METHODS - BURKE, MARQUES, and colleagues discuss anti-dengue NS1-specific IgG and IgG3 as potential biomarkers of long-term and recent (less than 6 months) DENV infections, respectively.  (06/14/2018)

Tradition and innovation in development of a Zika vaccine 

Tradition and innovation in development of a Zika vaccine

THE LANCET - MARQUES and BURKE comment about two Zika vaccines in clinical development and describe the challenges ahead. (06/14/2018)

Zika virus displacement by a chikungunya outbreak in Recife, Brazil 

Zika virus displacement by a chikungunya outbreak in Recife, Brazil

PUBLIC LIBRARY OF SCIENCE - Magalhaes, Braga, Cordeiro, Oliveira, Castanha, Maciel, Amancio, Gouveia, Peixoto-deSilva Jr., Peixoto, Britto, Lima, Lima, and Marques detected the tail end of a Zika epidemic in 2015-16 which was displaced by a chikungunya epidemic. Few dengue cases were identified des... (06/14/2018)

Rift Valley fever in animals and humans: Current perspectives 

Rift Valley fever in animals and humans: Current perspectives

ANTIVIRAL RESEARCH - McMillen and Hartman discuss the historical role of Rift Valley Fever (RVF) as a biological weapon and conclude with an outline of the important unanswered questions for ongoing research into this important zoonotic disease. (06/11/2018)

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN 

Inefficient HIV-1 trans infection of CD4+ T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN

JOURNAL OF VIROLOGY - Delucia, Rinaldo, Rappocciolo demonstrate that the use of SIMV to decrease macrophage-mediated virus transfer should be considered for future HIV therapeutic development.  (05/18/2018)

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury 

Human immunodeficiency virus type 1 (HIV-1)-mediated neuroinflammation dysredulates neurogranin and induces synaptodendritic injury

JOURNAL OF NEUROINFLAMMATION - Guha, Wagner, Ayyavoo conduct first study evaluating the potential role of Ng in the context of HIV-1 neropathogens and conclude that synaptic damage in HAND+ patients could be a result of abrogation of Ng through HIV-1 induced inflammation that dysregulates Ng-CaM in... (05/18/2018)

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques 

Widespread virus replication in alveoli drives acute respiratory distress syndrome in aerosolized H5N1 influenza infection of macaques

JOURNAL OF IMMUNOLOGY - Wonderlich, Swan, Bissel, Hartman, Carney, O'Malley, Obadan, Santos, Walker, Sturgeon, Frye, Maiello, Scanga, Bowling, Duangkhae, Wiley, Flynn, Wang, Cole, Reed, Barratt-Boyes establish a new nonhuman primate disease model for evaluation of vaccine and therapeutic approaches... (02/14/2018)

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IDM Videos

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Hartman among researchers trying to prevent virus more dangerous than Zika (video) 

Hartman among researchers trying to prevent virus more dangerous than Zika (video)

WPXI - Pitt researchers are looking to lessons learned about Zika when preparing for the possibility of Rift Valley Fever virus, noting that it's important to develop therapies and vaccines now. "We saw the ffects of Zika when it got into a larger population and so our work highlights the need to r... (02/11/2019)
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Hernandez's research adds to pharmaceutical industry's growing pressure over high price of drugs 

Hernandez's research adds to pharmaceutical industry's growing pressure over high price of drugs

FOX NEWS - "It's not about innovation, it's about inflation in existing products," explains Inmaculada Hernandez (HPM '16). "They are the same companies that operate in other countries and they don't show this behavior and that's because in other countries they are lucky to have this regulatory env... (01/24/2019)
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IDM’s Rinaldo discusses HIV wonder drugs and curing HIV in 1998 World AIDS Day interview (VIDEO) 

IDM’s Rinaldo discusses HIV wonder drugs and curing HIV in 1998 World AIDS Day interview (VIDEO)

UPMC HEALTH NEWS – In the late 1990s, new and highly potent anti-HIV drugs emerged— including protease and reverse transcriptase inhibitors—which could for the first time control HIV infection. For this 1998 World AIDS Day, Pitt IDM AIDS researcher Charles Rinaldo and the late Bridget Murtagh of th... (07/17/2018)
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Matthews on why we need a public health approach to HIV (video) 

Matthews on why we need a public health approach to HIV (video)

IDM's DERRICK MATTHEWS explains Pitt Public Health's work on HIV/AIDS and where we are today. "If your’e a black gay man in the U.S., you have a one in two change in your lifetime of becoming HIV positive…short of the cure that we’re looking for, the biology is way ahead of the social implementat... (06/20/2018)
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