Research Instructor, Environmental and Occupational Health
130 DeSoto Street, Pittsburgh, PA 1561
Primary Phone: 967-179-4929
My research interest is focused on searching new compounds that can mitigate and/or treat the short- and long-term consequences of severe irradiation exposure such as radiological/nuclear terrorist event. Though irradiation directly induces serious damage to rapidly proliferating cells, the subsequent mechanisms of damage seem to be triggered by secondary responses whereby inflammatory cytokines, chemotactic factors and lipid mediators are the major players. More and more evidences showed that cells were damaged by irradiation directly or indirectly through necroptotic pathway. Lipids were reported to play an important role during necroptosis. My goal is to find lipid mediators during primary or secondary irradiation induced necroptosis, and search new compounds protect cells from damage by blocking the lipid mediators' signaling pathway.
2005 | Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Bejing, China | PhD in Pharmacognosy
1996 | Shandong University, China | Bachelor of Science in Microbiology