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Ying Ding, PhD

Assistant Professor, Biostatistics

Contact

7133 Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261
R-znvy: lvatqvat@cvgg.rqh
Primary Phone: 967-179-4952


Personal Statement

My primary research interests include semiparametric methods and inferences, especially for time-to-event data; subgroup analysis such as simultaneous inference and biomarker/subgroup identification. Currently, my collaborative research focuses on proteomic experiment design, network analysis for psychiatric disorders and progression analysis of AMD (Age-related Macular Degeneration).


Education

Ph.D. (2010) Department of Biostatistics, University of Michigan, MI
M.A. (2005) Department of Mathematics, Indiana University Bloomington, IN
B.S. (2003) Department of Mathematics, Nanjing University, China


Teaching

Survival Analysis BIOST2054/STAT2261 Spring 2018
Applied Mixed Models BIOST2086 Spring 2013, Spring 2014, Spring 2016, 2017
Biostatistics Seminar  BIOST2025 Spring 2014, Fall 2014


Research Funding

  1. Funding Agency: UPMC 
    Grant Title: Competitive Medical Research Fund
    Role on Grant:: Principal Investigator
    Years Inclusive: 7/1/2015 - 12/31/2017
    Total Direct Costs: $25,000                                                                  
  2. Funding Agency: NIH/NIMH
    Grant Number: R03MH108849
    Grant Title: Novel and Robust Methods for Differential Protein Network Analysis of Proteomics Data in Schizophrenia 
    Research
    Role on Grant:: Principal Investigator
    Years Inclusive: 7/1/2016 – 6/30/2018
    Total Direct Costs: $100,000


Selected Publications

*: corresponding author; +: co-first author; _: students 

  1. Yan Q, Ding Y+Liu Y, Sun T, Fritsche LG, Clemons T, Ratnapriya R, Klein ML, Cook RJ, Liu Y, Fan R, Wei L, Abecasis GR, Swaroop A, Chew EY, AREDS2 research group, Weeks  DE, Chen W. (2018) Genome-wide Analysis of Disease Progression in Age-related Macular Degeneration. Human Molecular Genetics. Accepted.
  2. Ding Y*, Li GY, Liu Y, Ruberg SJ, Hsu JC. (2018). Confident Inference For SNP Effects On Treatment Efficacy. Annals of Applied Statistics. In Press. 
  3. Sun Z, Wang T, Deng K, Wang X-F, Lafyatis R, Ding Y, Hu M, Chen W. (2017). DIMM-SC: A Dirichlet mixture model for clustering droplet-based single cell transcriptomic data. Bioinformatics. doi: 10.1093/bioinformatics/btx490 PMID: 29036318
  4. Ding Y, Liu Y, Yan Q, Fritsche LG, Cook RJ, Clemons T, Ratnapriya R, Klein ML, Abecasis GR, Swaroop A, Chew EY, Weeks DE, Chen W. (2017). Bivariate Analysis of Age-Related Macular Degeneration Progression Using Genetic Risk Scores. Genetics. 206(1):119-133. . PMID: 28341650. Received editorial highlights and media reports.
  5. Ding Y*, Lin HM. Data Analysis of in vivo Fluorescence Imaging Studies. In: Bai M, editors. In Vivo Fluorescence Imaging: Methods and Protocols. New York: Springer, 2016.
  6. Wang T, Ren Z, Ding Y, Zhou F, Sun Z, MacDonald ML, Sweet RA, Chen W. (2016). FastGGM: An efficient algorithm for the inference of Gaussian graphical model in biological networks. PLoS Computational Biology. 12(2): e1004755. PMID: 26872036
  7. Fan R, Wang Y, Yan Q, Ding Y, Weeks DE, Lu Z, Ren H, Cook R J, Xiong M, Swaroop A, Chew E Y, and Chen W. (2016). Gene-based Association Analysis for Censored Traits Via Fixed Effect Functional Regressions. Genetic Epidemiology. 40(2): 133-43. PMID: 26782979
  8. Ding Y*, Lin HM, Hsu JC. (2016). Subgroup Mixable Inference on Treatment Efficacy in Mixture Populations, with an Application to Time-to-Event Outcomes. Statistics in Medicine. 35(10):1580-94. PMID: 26646305
  9. Ding Y*, Nan B. (2015). Estimating Mean Survival Time: When is it Possible? Scandinavian Journal of Statistics 42(2):397-413. PMID: 26019387 PMCID: PMC4442028
  10. Shen L, Ding Y, Battioui C. A Framework of Statistical Methods for Identification of Subgroups with Differential Treatment Effects in Randomized Trials. (2015) In: Chen Z, Liu A, Qu Y, Tang L, Ting N & Tsong Y, eds. Applied Statistics in Biomedicine and Clinical Trials Design: Selected Papers from 2013 ICSA/ISBS Joint Statistical Meetings. New York: Springer.
  11. Peng J, Ding Y+, Tu S, Lu JJ, Shi D., Chen W, Li X, Wu H, Cai S. (2014). Prognostic nomograms for predicting survival and distant metastases in locally advanced rectal cancers without neoadjuvant treatment. PloS One 9(8):e106344. PMID: 25171093
  12. Ding Y*, Fu H. (2013). Bayesian Indirect and Mixed Treatment Comparisons Across Longitudinal Time Points. Statistics in Medicine 32 (15):2613-28. PMID: 23229717
  13. Banerjee M, Ding Y, Noone A. (2012). Identifying Representative Trees from Ensembles. Statistics in Medicine 31(15):1601-16.  PMID: 22302520
  14. Ding Y, Nan B. (2011). A Sieve M-theorem for Bundled Parameters in Semiparametric Models, with Application to the Efficient Estimation in a Linear Model for Censored Data. Annals of Statistics 39(6): 3032-3061. PMID: 24436500  PMCID:  PMC3890689
  15. Ding Y, Choi H, Nesvizhskii AI. (2008). Adaptive Discriminant Function Analysis and Reranking of MS/MS Database Search Results for Improved Peptide Identification in Shotgun Proteomics. Journal of Proteome Research 7(11): 4878-89.  PMID: 18788775  PMCID: PMC3744223

Complete List of Published Work in My Bibliography:
http://www.ncbi.nlm.nih.gov/sites/myncbi/1f510URSbxjQh/bibliography/47222780/public/?sort=date&direction=ascending

Ying   Ding
© 2018 by University of Pittsburgh Graduate School of Public Health

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