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Ryan L. Minster, PhD, MSIS

Assistant Professor, Human Genetics

Contact

A302A Parran Hall
R-znvy: ezvafgre@cvgg.rqh
Primary Phone: 967-179-1473


Personal Statement

Dr Minster is a genetic epidemiologist who focuses on the genetics of complex traits such as body composition, obesity and healthy aging. He is particularly interested in pleiotropic relationships among complex phenotypes such as those between bone mineral density and geometry, lean muscle mass and fat mass. He is also interested in evidence of selection in population isolates and their impact on human disease.


Education

1998 | University of Pittsburgh, Pittsburgh, PA | Bachelor of Science, Molecular Biology
2003 | University of Pittsburgh, Pittsburgh, PA | Master of Science in Information Science
2011 | University of Pittsburgh, Pittsburgh, PA | Doctor of Philosophy, Human Genetics


Teaching

Bioinformatics Resources for Geneticists | HUGEN 2010
Bioinformatics for Human Genetics | HUGEN 2070
Statistical Genetics | HUGEN 2080
Public Health Biology | PUBHLT 2015
Capstone: Problem Solving in Public Health | PUBHLT 2016


Selected Publications

S.A. Sherman, R.J. Rogers, K.K. Davis, R.L. Minster, S.A. Creasy, N.C. Mullarkey, M. O’Dell, P. Donahue, J.M. Jakicic. Energy expenditure in vinyasa yoga versus walking. J. Phys. Act. Health 19, 1–29 (2017).
DOI: 10.1123/jpah.2016-0548

J. Singh, R.L. Minster, N. Schupf, A. Kraja, Y. Liu, L. Christensen, A.B. Newman, C.M. Kammerer. Genomewide association scan of a mortality associated endophenotype for a long and healthy life in the Long Life Family Study. J. Gerontol. A Biol. Sci. Med. Sci. in press.
DOI: 10.1093/gerona/glx011

 

R.L. Minster, N.L. Hawley, C.-T. Su, G. Sun, E.E. Kershaw, H. Cheng, O.D. Buhule, J. Lin, M.S. Reupena, S. Viali, J. Tuitele, T. Naseri, Z. Urban, R. Deka, D.E. Weeks, S.T. McGarvey. A thrifty variant in CREBRF strongly influences body mass index in Samoans. Nat. Genet. 48, 1049–54 (2016).

DOI: 10.1038/ng.3620

 

J.L. Sanders, J. Singh, R.L. Minster, J.D. Walston, A.M. Matteini, K. Christensen, R. Mayeux, I.B. Borecki, T. Perls, A.B. Newman. Association Between Mortality and Heritability of the Scale of Aging Vigor in Epidemiology. J. Am. Geriatr. Soc. 64, 1679–83 (2016).
DOI: 10.1111/jgs.14190

 

R.L. Minster, J.L. Sanders, J. Singh, C.M. Kammerer, M.M. Barmada, A.M. Matteini, Q. Zhang, M.K. Wojczynski, E.W. Daw, J.A. Brody, A.M. Arnold, K.L. Lunetta, J.M. Murabito, K. Christensen, T.T. Perls, M.A. Province, & A.B. Newman. Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index. J. Gerontol. A Biol. Sci. Med. Sci. 70, 1003–8 (2015).
DOI: 10.1093/gerona/glv006


B.A. Kozel, C.-T. Su, J.R. Danback, R.L. Minster, S. Madan-Khetarpal, J. McConnell, M.K. Mac Neal, K.L. Levine, R.C. Wilson, R.C. Sciurba & Z. Urban. Biomechanical properties of the skin in cutis laxa. J. Invest. Dermatol. 134, 2836–8 (2014).
DOI: 10.1038/jid.2014.224

O.D. Buhule, R.L. Minster, N.L. Hawley, M. Medvedovic, G. Sun, S. Viali, R. Deka, S.T. McGarvey, D.E. Weeks. Stratified randomization controls better for batch effects in 450K methylation analysis: a cautionary tale. Front. Genet. 5, 354 (2014).
DOI: 10.3389/fgene.2014.00354

 

N.L. Hawley, R.L. Minster, D.E. Weeks, S. Viali, M.S. Reupena, G. Sun, H. Cheng, R. Deka & S.T. McGarvey. Prevalence of adiposity and associated cardiometabolic risk factors in the Samoan Genome-Wide Association Study. Am. J. Hum. Biol. 26, 491–501 (2014).
DOI: 10.1002/ajhb.22553

A. Moayyeri, Y.-H. Hsu, D. Karasik, K. Estrada, S.-M. Xiao, C. Nielson, P. Srikanth, S. Giroux, S.G. Wilson, H.-F. Zheng, A.V. Smith, S.R. Pye, P.J. Leo, A. Teumer, J.-Y. Hwang, C. Ohlsson, F. McGuigan, R.L. Minster, C. Hayward, J.M. Olmos, L.-P. Lyytikäinen, J.R. Lewis, K.M.A. Swart, L. Masi, C. Oldmeadow, E.G. Holliday, S. Cheng, N.M. van Schoor, N.C. Harvey, M. Kruk, M. Fabiola Del Greco, W. Igl, O. Trummer, E. Grigoriou, R. Luben, C.-T. Liu, Y. Zhou, L. Oei, C. Medina-Gomez, J. Zmuda, G. Tranah, S.J. Brown, F.M. Williams, N. Soranzo, J. Jakobsdottir, K. Siggeirsdottir, K.L. Holliday, A. Hannemann, M.J. Go, M. Garcia, O. Polasek, M. Laaksonen, K. Zhu, A.W. Enneman, M. McEvoy, R. Peel, P.C. Sham, M. Jaworski, Å. Johansson, A.A. Hicks, P. Pludowski, R. Scott, R.A.M. Dhonukshe-Rutten, N. van der Velde, M. Kähönen, J.S. Viikari, H. Sievänen, O.T. Raitakari, J. González-Macías, J.L. Hernández, D. Mellström, Ö. Ljunggren, Y.S. Cho, U. Völker, M. Nauck, G. Homuth, H. Völzhe, R. Haring, M.A. Brown, E. McCloskey, G.C. Nicholson, R. Eastell, J.A. Eisman, G. Jones, I.R. Reid, E.M. Dennison, J. Wark, S. Boonen, D. Vanderschueren, F.C.W. Wu, T. Aspelund, J.B. Richards, D. Bauer, A. Hofman, K.-T. Khaw, G. Dedoussis, B. Obermayer-Pietsch, U. Gyllensten, P.P. Pramstaller, R.S. Lorenc, C. Cooper, A.W.C. Kung, P. Lips, M. Alen, J. Attia, M.L. Brandi, L.C, de Groot, T. Lehtimäki, J.A. Riancho, H. Campbell, Y. Liu, T.B. Harris, K. Akesson, M. Karlsson, J.-Y. Lee, H. Wallaschofski, E.L. Duncan, T.W. O'Neill, V. Gudnason, T.D. Spector, F. Rousseau, E. Orwoll, S. Cummings, N.J. Wareham, F. Rivadeneira, A.G. Uitterlinden, R.L. Prince, D.P. Kiel, J. Reeve & S.K. Kaptoge. Genetic determinants of heel bone properties: Genome-wide association meta-analysis and replication in the GEFOS/GENOMOS Consortium. Hum. Mol. Genet. 23, 3054–68 (2014).
DOI: 10.1093/hmg/ddt675

J.L. Sanders, R.L. Minster, M.M. Barmada, A.M. Matteini, R.M. Boudreau, K. Christensen, R. Mayeux, I.B. Borecki, Q. Zhang, T. Perls & A.B. Newman. Heritability of and mortality prediction with a longevity phenotype: the Healthy Aging Index. J. Gerontol. A Biol. Sci. Med. Sci. 69, 479–85 (2014).
DOI: 10.1093/gerona/glt117

Ryan L. Minster
© 2017 by University of Pittsburgh Graduate School of Public Health

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