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Marnie Bertolet, PhD

Assistant Professor, Epidemiology

Assistant Professor, Biostatistics

Assistant Professor, Clinical and Translational Science Institute

Contact

4420 Bayard Street, Suite 600, University of Pittsburgh, PIttsburgh, Pa 15260
R-znvy: zuo67@cvgg.rqh
Primary Phone: 967-193-2543


Personal Statement

Research Interests 


My research interests focus on the many uses of statistics in public health.  My devotion to statistics stems from the diversity of applications to which statistics can be applied.  I came to public health after a career in telecommunications, where I was a reliability and quality engineer performing analyses analogous to “consumer reports” for telecommunication equipment. 

My collaborative research currently focuses longitudinal, repeated measure and survival analysis methods in clinical trials and observational studies. Examples include:

  • Cardiovascular and Diabetes Epidemiology
  • Pulmonary Function in the HIV+ Community
  • Child and Maternal Health

My methodological research currently focuses Survey Sampling, Bayesian Analysis, Causal Inference, Adaptive Designs and methodology needed to support my collaborative research.  This includes the following topics

  • Inverse probability weight modeling
  • Bayesian interim monitoring of clinical trials
  • Classification and Regression Trees
  • Bayesian latent class models

My research support comes from the following sources.

  • The Trans-Agency Research Consortium for Trauma Induced Coagulopathy (TACTIC, NIH/NHLBI)
  • Translational Evaluation of Aging, Inflammation and HIV in Lung Dysfunction (NHI/NHLBI)
  • Clinical and Translational Science Institute DBE Core (NIH)


Honors and Awards 

  • Certificate in Teaching Excellence from the University of Pittsburgh Graduate School of Public Health
  • Student of the Year Award, American Statistical Association, Pittsburgh Chapter 2008 
  • Health Policy Student Paper Award, Joint Statistical Meetings, American Statistical Association, 2004 
  • Most Outstanding Master of Engineering Student Award  Cornell University 1995


Education

Education & Training 

  • Carnegie Mellon University – Ph.D. Statistics, 2008 
  • Carnegie Mellon University – M.S. Statistics, 2002  
  • Cornell University, M.Eng. Operations Research and Industrial Engineering, 1995
  • Shippensburg University – B.A. Mathematics, 1993


Teaching

Teaching 
My teaching focuses on statistical methods in epidemiology.  In addition to mentoring students and participating on student committees, I teach the following courses:


  • Fall Term: University of Pittsburgh, EPIDEM 2181 – Design of Clinical Trials 
  • Fall Term: University of Pittsburgh, EPIDEM 2215 – Teaching Practicum

To keep up to date with new teaching practices, I attend many of the CIDDE (center for instructional development and distance education) courses on good teaching practices.  I specifically focus on using active learning techniques within the classroom.  I also participated in two programs to further my teaching education:


  • Carnegie Mellon University – Documentation of Teaching Effectiveness – 2008
  • Graduate School of Public Health – University of Pittsburgh  - Certificate of Teaching Excellence – 2012


Service

Service
My service varies from reviewing journal articles, participating in grant reviews and serving on various local and national committees.  I see service as an excuse to expose as many people as possible to the wonderful power of statistics.  

I reviewed journal articles for the following journals in 2015-2016

  • Circulation
  • Women’s Health Issues
  • American Journal of Psychiatry
  • Journal of Clinical Psychiatry

I have participated as an ad-hoc member in the following NIH grant/contract reviews

  • Grand Opportunities Phase II ARRA Grants
  • Science Moving Towards Research Translation and Therapy 
  • Claude D. Pepper Older American Independence Centers (P30 Center Core Grant)


I have participated in the following committees

  • GSPH School wide Acceptance Students Day 
  • GSPH School-wide Dean’s Day Judge
  • Biostatistics Department Public Health Preliminary Exam Committee
  • Epidemiology Department Preliminary Exam Committee

Local Service

  • President of the Pittsburgh Chapter of the American Statistical Association, 2013-2014

 National Service 

  • ACCF/AHA Methodology Workshop on Guideline Development and Methodology Review
  • President of the Pittsburgh Chapter of the American Statistical Association, 2013-2014


Selected Publications

First Author Publications, High Impact Publications and Publications between 2015-2016

Ray KN, Chari AV, Engberg J, Bertolet M, Mehrotra A. Opportunity costs of ambulatory medical care in the United States. The American Journal of Managed Care. 2015 Aug; 21 (8):567-74. PMID: 26295356.


Bittner V, Bertolet M, Barraza Felix R, Farkouh ME, Goldberg S, Ramanathan KB, Redmon JB, Sperling L, Rutter MK, BARI 2D Study Group.Comprehensive Cardiovascular Risk Factor Control Improves Survival: The BARI 2D Trial. Journal of The American College of Cardiology. 2015 Aug 18; 66 (7):765-73. PMCID: PMC4550809. PMID: 26271057. doi: 10.1016/j.jacc.2015.06.019.


 Ristau BT, Tomaszewski JJ, Chen YF, Bertolet M, Woldemichael E, Nelson JB. Prostate biopsy perineural invasion is not independently associated with positive surgical margins following radical retropubic prostatectomy. World Journal of Urology. 2015 Sep; 33 (9):1269-74. PMID: 25366883. doi:10.1007/s00345-014-1430-2.


Ray KN, Chari AV, Engberg J, Bertolet M, Mehrotra A. Disparities in Time Spent Seeking Medical Care in the United States. JAMA Internal Medicine. 2015 Dec; 175 (12):1983-6. PMID: 26437386. doi: 10.1001/jamainternmed.2015.4468.

Bertolet M, Brooks MM, Bittner V. Tree-based identification of subgroups for time-varying covariate survival data. Statistical methods in medical research. 2016 Feb; 25 (1):488-501. PMID: 23070595. doi: 10.1177/0962280212460442.


Wolk R, Bertolet M, Singh P, Brooks MM, Pratley R, Frye R, Mooradian A, Rutter M, Calvin A, Chaitman B, Somers V. Prognostic Value of Adipokines in Predicting Cardiovascular Outcome- Explaining the Obesity Paradox. Mayo Clinic Proceedings. (in Press)


Jacobs AK, Kushner FG, Ettinger SM, Guyton RA, Anderson JL, Ohman EM, Albert NM, Antman EM, Arnett DK, Bertolet M, Bhatt DL, Brindis RG, Creager MA, DeMets DL, Dickersin K, Fonarow GC, Gibbons RJ, Halperin JL, Hochman JS, Koster MA, Normand SL, Ortiz E, Peterson ED, Roach WH Jr, Sacco RL, Smith SC Jr, Stevenson WG, Tomaselli GF, Yancy CW, Zoghbi WA, Harold JG, He Y, Mangu PB, Qaseem A, Sayre MR, Somerfield MR. ACCF/AHA clinical practice guideline methodology summit report: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Journal of the American College of Cardiology. 2013 Jan 15; 61 (2):213-65. PMID: 23238451.

 Jacobs AK, Kushner FG, Ettinger SM, Guyton RA, Anderson JL, Ohman EM, Albert NM, Antman EM, Arnett DK, Bertolet M, Bhatt DL, Brindis RG, Creager MA, DeMets DL, Dickersin K, Fonarow GC, Gibbons RJ, Halperin JL, Hochman JS, Koster MA, Normand SL, Ortiz E, Peterson ED, Roach WH Jr, Sacco RL, Smith SC Jr, Stevenson WG, Tomaselli GF, Yancy CW, Zoghbi WA. ACCF/AHA clinical practice guideline methodology summit report: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013 Jan 15; 127 (2):268-310. PMID: 23230312.


Marnie  Bertolet
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