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Dr. Elizabeth R Wonderlich, PhD


R-znvy: rjw0@cvgg.rqh
Primary Phone: 967-838-4502


2004 | Pennsylvania State University, University Park, PA | B.S.    

2010 | University of Michigan, Ann Arbor, MI | Ph.D.                               

Legal Name

Elizabeth Wonderlich Janci


Selected Publications

Wonderlich, E.R., Williams, M., and Collins, K.L.  (2008) The Tyrosine Binding Pocket in the Adaptor Protein 1 (AP-1) µ1 Subunit Is Necessary for Nef to Recruit AP-1 to the Major Histocompatibility Complex Class I Cytoplasmic Tail.   J. Biol. Chem. 283 (6): 3011-3022. PMID: 18073204


Schaefer, M.R., Wonderlich, E.R., Roeth, J.F., Leonard, J.A., and Collins, K.L. (2008) HIV-1 Nef targets MHC-I and CD4 for degradation via a final common b-COP-dependent pathway in T Cells.  PLoS Pathogens. 4(8):e1000131. PMID: 18725938


Wonderlich, E.R., Leonard, J.A., and Collins, K.L. (2011) HIV Immune Evasion: Disruption of Antigen Presentation by the HIV Nef Protein. Adv Virus Res. 2011;80:103-27. PMID: 21762823


Wonderlich, E.R., Kader, M., Wijewardana, V., and Barratt-Boyes, S.M. (2011) Dissecting the Roles of Dendritic Cells in Simian Immunodeficiency Virus Infection and AIDS. Immunol Res. 2011 Aug;50(2-3):228-34. PMID: 21717075


Wonderlich E.R., Leonard J.A., Kulpa  D.A., Leopold K.E., Norman J.M., Collins K.L. (2011) ADP ribosylation factor 1 activity is required to recruit AP-1 to the major histocompatibility complex class I (MHC-I) cytoplasmic tail and disrupt MHC-I trafficking in HIV-1 infected primary T cells.  J. Virol.  2011 Dec;85(23):12216-26. PMID: 21917951


Wonderlich E.R., Barratt-Boyes S.M. (2012) A dendrite in every pie: Myeloid dendritic cells in HIV and SIV infection. Virulence. 2012 Nov 15;3(7). PMID: 23154284


Wonderlich E.R., Wijewardana V., Liu X., Barratt-Boyes S.M. (2013) Virus-Encoded TLR Ligands Reveal Divergent Functional Responses of Mononuclear Phagocytes in Pathogenic Simian Immunodeficiency Virus Infection. J Immunol. 2013 Mar 1;190(5):2188-98. PMID: 23338235


Kader M., Smith A.P., Guiducci C., Wonderlich E.R., Normolle D., Watkins S.C., Barrat F.J., Barratt-Boyes S.M. (2013) Blocking TLR7- and TLR9-mediated IFN-α Production by Plasmacytoid Dendritic Cells Does Not Diminish Immune Activation in Early SIV Infection. PLoS Pathog 9(7): e1003530. doi:10.1371/journal.ppat.1003530 PMID: 23935491


Wonderlich E.R., Barratt-Boyes S.M. (2013) SIV infection of rhesus macaques differentially impacts mononuclear phagocyte responses to virus-derived TLR agonists. J Med Primatol. 2013 Oct;42(5):247-53. PMID: 23905748

Wonderlich E.R., Wu W.C., Normolle, D., Barratt-Boyes S.M. Macrophages and Myeloid
Dendritic Cells Lose T Cell-Stimulating Function in Simian Immunodeficiency
Virus Infection Associated with Diminished IL-12 and IFN-a Production. J Immunol.
2015 Oct 1;195(7):3284-92. PMID:26297760


Swan Z.D., Wonderlich E.R., Barratt-Boyes S.M. Macrophage accumulation in gut mucosa differentiates AIDS from chronic SIV infection in rhesus macaques. Eur J Immunol. 2015 Nov 9. PMID:26549608


Elizabeth R Wonderlich
© 2018 by University of Pittsburgh Graduate School of Public Health

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