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Dr. Dietrich A Stephan, PhD

CEO and Founder, LifeX™

Professor, Human Genetics

Chief Innovation Officer, Center for Machine Learning and Health, Carnegie Mellon University

Associate Director for Population Genetics and Translational Acceleration , Institute for Personalized Medicine of UPMC & University of Pittsburgh Health Sciences


2730 Sydney Street, Third Floor, Pittsburgh, PA 15203
R-znvy: qfgrcuna@cvgg.rqh
Primary Phone: 967-193-8808
Web site:

Personal Statement

Dr. Dietrich Stephan, Ph.D., is a renowned geneticist and entrepreneur, recognized for his early leadership the field of Precision Medicine. Stephan is a Professor of Human Genetics at the University of Pittsburgh and also President and CEO of LifeX, an impact platform for improving the human condition. Profiled twice on the front page of the Wall Street Journal for his seminal contributions to mankind, Stephan’s solutions are improving lives across the globe.


1991 | Carnegie Mellon University, Pittsburgh, PA | Bachelor of Science

1996 | University of Pittsburgh, Pittsburgh, PA | Doctor of Philosophy

1999 | National Human Genome Research Institute | Fellow


Translating Scientific Insights into Medical Products

Leadership in Biotechnology

Communicating Effectively as a Scientist


Selected Publications

Dunckley T, Huentelman MJ, Craig DW, Pearson JV, Szelinger S, Joshipura K, Halperin RF, Stamper C, Jensen KR, Letizia D, Hesterlee SE, Pestronk A, Levine T, Bertorini T, Graves MC, Mozaffar T, Jackson CE, Bosch P, McVey A, Dick A, Barohn R, Lomen-Hoerth C, Rosenfeld J, O’Connor DT, Zhang K, Crook R, Ryberg H, Hutton M, Katz Jonathan, Simpson E, Mitsumoto H, Bowser R,
Miller RG, Appel SH and Stephan DA.  Whole-genome analysis of Sporadic Amyotrophic Lateral Sclerosis.  New Engl J Med.  2007 Aug 23; 357(8): 775-788.

Liang WS, Reiman EM, Valla J, Dunckley T, Beach TG, Grover A, Niedzielko TL, Schneider LE, Mastroeni D, Caselli R, Kukull W, Morris JC, Hulette C, Schmechel D, Rogers J and Stephan DA.  Alzheimer’s disease is associated with reduced expression of energy metabolism genes in posterior cingulated neurons.  Proc Natl Acad Sci.  2008 March 18; 105(11):4441-4446.

Padhukasahasram B, Halperin E, Wessel J, Thomas DJ, Silver E, Trumbower H, Schork NJ, Cargill M, Stephan DA. Pre-symptomatic risk assessment for chronic non-communicable diseases.  PLoS One. 2010 Dec 31;5(12):e14338.

Ghadar F, Sviokla J, Stephan DA. Why life science needs Its own Silicon Valley. Harv Bus Rev. 2012 Jul-Aug;90(7-8):25-7.

Dietrich A Stephan
© 2018 by University of Pittsburgh Graduate School of Public Health

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