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Balasubramani K Goundappa, PhD

Research Assistant Professor/Senior Statistician, Epidemiology

Contact

Epidemiology Data Center, 4420 Bayard Street, Suite 600, Pittsburgh, PA 15260
R-znvy: onyntx@rqp.cvgg.rqh
Primary Phone: 967-193-7170
Fax: 967-179-8220


Personal Statement

I have the experience and training in the analysis of large clinical trial data particularly on Traumatic Brain injury in children a phase 3 randomized controlled trial research and as key personnel for the ongoing international trial on the Approaches and Decision in Acute Pediatric TBI (ADAPT) trial at the Epidemiology Data Center, University of Pittsburgh. I have the expertise in the area of statistical methodologies for clinical trials and am distinctively suited to the proposed study. I have the leadership skill and essential desire to effectively accomplish the work. I was involved in the development of study designs, managed and analyzed data for two federally funded national studies on the determination of effective treatment modalities for non-psychotic major depressive disorders, and mortality rates for HIV patients challenged with respiratory conditions. I have broad background knowledge in statistics, with specific training and expertise in key research areas of major depression
disorder, traumatic brain injury and HIV and pulmonary complications. I have work together with several investigators on the study design, contributes to protocol development and analysis of clinical trials in a number of different medical disciplines including major depression disorder, pulmonary infection with HIV, medical condition associated with endotracheal intubation and
traumatic brain injury. As a key personnel or co-investigator on several NIH funded grants, I have developed efficient research methodologies for several epidemiological studies of major significance for public health. I have coauthored several peer-reviewed publications from each project.



Education

1995 | University of Western Ontario, Canada | Post-Doctoral Training in Actuarial Statistics
1992 | University of Madras, India | Doctor of Philosophy, Statistics
1987 | University of Madras, India | Masters of Philosophy
1986 | University of Madras, India | Masters of Science, Statistics
1984 | Presidency College, India | Bachelor's of Science, Statistics


RESEARCH INTEREST

My clinical trial research focused on statistical and epidemiological investigations of clinical
trial data from large multicenter clinical trials. My current research are in development and application of statistical methodologies are on, (i) Genomic Research in Alpha 1 anti-trypsin (A1AT) deficiency and Sarcoidosis, (ii) Approaches and decisions for acute pediatric traumatic brain injury trial
and (iii) Study on the vaccine effectiveness of Influenza and other respiratory virus infections in outpatients with medically attended acute respiratory infection, US Flu Network study.


GRANTS

1. Role: EDC Principal Investigator

Title: Flu vaccine effectiveness in those hospitalized in large diverse health system.

Funding Agency: CDC. Period: July 1, 2015 – August, 2020.  

2.  Role: Principal Investigator-Data Coordinating Center

Title: Influenza Vaccine Effectiveness for Preventing Medically Attended Laboratory-Confirmed Influenza in the United States 

Funding Agency: CDC Period: 08/01/2016-07/31/2021 

3. Role: Principal Investigator-Data Coordinating Center

Title: Enhanced Surveillance for New Vaccine Preventable Disease – The New Vaccine Surveillance Network (NVSN)

Funding Agency: CDC : Period: 09/30/2016- 08/31/2021                                            

4.   Role: PI

Title:Glaucoma Management in the African-Derived Developing World Using Laser Trabeculoplasty
Contracting Firm: West Virginia University Research Corporation
Funding Agency: NIH- R01 EY023620
Period: September 01, 2015- August 31, 2020

 


Selected Publications

1.     Vargo JA, Ghareeb ER, Balasubramani GK, Beriwal S. RE: Adjuvant Radiation Therapy and Chemotherapy in Merkel Cell Carcinoma: Survival Analyses of 6908 Cases From the National Cancer Data Base. Journal of National Cancer Institute 2017 Oct 1;109(10). doi: 10.1093/jnci/djx052. PMID: 28423400.

2.     John A. Vargo, Arisha Patel, Scott M Glaser,  Balasubramani GK, Rafic J Farah, Stanley M Marks, Sushil Beriwal: The impact of the omission or Inadequate dosing of radiotherapy in Extra-nodal Natural Killer T-cell Lymphoma, Nasal Type in the United States. Cancer. 2017 Apr 5. doi: 10.1002/cncr.30697. PMID:28380259.

3.     Glaser SM, Dohopolski MJ, Balasubramani GK, Benoit RM, Smith RP, Beriwal S. Brachytherapy boost for prostate cancer: Trends in care and survival outcomes. Brachytherapy. 2017 Feb 1. pii: S1538-4721(17)30004-1. doi: 10.1016/j.brachy.2016.12.015. PMID: 28159553.

4.     Zimmerman RKNowalk MPChung JJackson MLJackson LAPetrie JGMonto ASMcLean HQBelongia EAGaglani MMurthy KFry AMFlannery B;U.S. Flu VE Investigators. Collaborators  : Balasubramani GKBurke DSChabra RGarafolo EIozzi PKevish BMiddleton DBOlbrich CReis ECSauereisen SUrbanski L,Wisniewski SAmaza HAndersen BArmagost ECerne YCole DCushman KDrowatzky SGilge KGillaspie WGreenwald GHerkert K,Hilgemann DJohnson TJoosse BKopitzke SKrenzke AMathews KMinervini MMoon VMurray SPilsner RPolacek DRetzlaff Z,Rottscheit CSalzwedel JSchultz KSchultz TSmith AStrey SVerhagen LVittallo KWesely JWirkus KStockwell PAnderson JOlson BHoxha KBeeram MReis MArroliga AWesson DPruszynski JRobertson ANagrani ASleeth PGandy VPonder TKylberg M,Gonzales HZayed MFurze DRay JRotoscykj JCryer GBullota AEng HFord SGray JMoehling KKRaviotta JMRicci EMRinaldo C,Saul SSax TSusick MKiniry EBenoit JPhillips CHOhmit SEMartin ETMalosh REMcSpadden EJCheng CKTruscon RJohnson E,Lamerato LELipkovich HRKing JPMeece JKIvacic LBertz PPruszyunski JClipper LRobertson APiedra PAAvadhanula VSpencer S,Berman LFoust ASessions WThaker SN.: 2014-2015 Influenza Vaccine Effectiveness in the United States by Vaccine Type. Clin Infect Dis. 2016 Dec 15:63(12): 1564-1573. PMID: 27702768

5.     Strange C, Senior RM, Sciurba F, O'Neal S, Morris A, Wisniewski SR, Bowler R, Hochheiser HS, Becich MJ, Zhang Y, Leader JK, Methé BA, Kaminski N, Sandhaus RA; GRADS Alpha-1 Study Group. Rationale and Design of the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis Study. Alpha-1 Protocol. Ann Am Thorac Soc. 2015 Oct;12(10):1551-60. doi: 10.1513/AnnalsATS.201503-143OC. PMID: 26153726

6.     Moller DR, Koth LL, Maier LA, Morris A, Drake W, Rossman M, Leader JK, Collman RG, Hamzeh N, Sweiss NJ, Zhang Y, O'Neal S, Senior RM, Becich M, Hochheiser HS, Kaminski N, Wisniewski SR, Gibson KF; GRADS Sarcoidosis Study Group. Rationale and Design of the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis (GRADS) Study. Sarcoidosis Protocol. Ann Am Thorac Soc. 2015 Oct;12(10):1561-71. doi: 10.1513/AnnalsATS.201503-172OT. PMID: 26193069.

7.     Zimmerman RK, Balasubramani GK, Nowalk MP, Eng H, Urbanski L, Jackson ML, Jackson LA, McLean HQ, Belongia EA, Monto AS, Malosh RE, Gaglani M, Clipper L, Flannery B, Wisniewski SR. Classification and Regression Tree (CART) analysis to predict influenza in primary care patients. BMC Infect Dis. 2016 Sep 22;16(1):503. PMID: 27659721.

8.     Glaser SM, Vargo JA, Balasubramani GK, Beriwal S. Stage II Testicular Seminoma: Patterns of Care and Survival by Treatment Strategy. Clin Oncol (R Coll Radiol). 2016 Aug; 28(8): 513-521. Doi: 10.1016/j.clon.2016.02.008. PMID: 27146264

9.     Ling DC, Vargo JA, Balasubramani GK, Beriwal S. Underutilization of radiation therapy in early-stage marginal zone lymphoma negatively impacts overall survival. Pract Radiat Oncol. 2016 Jul-August; 6(4):e97-e105. Doi: 10.1016/j.prro.2015.11.016. PMID: 26852172.

10.  Hwang YG, Balasubramani GK, Metes ID, Levesque MC, Bridges SL Jr, Moreland LW. Differential response of serum amyloid A to different therapies in early rheumatoid arthritis and its potential value as a disease activity biomarker. Arthritis Res Ther. 2016 May 17;18(1):108. doi: 10.1186/s13075-016-1009-y. PMID:27188329.

11.  Horne ZD, Glaser SM, Vargo JA, Ferris RL, Balasubramani GK, Clump DA, Heron DE, Beriwal S. Confirmation of proposed human papillomavirus risk-adapted staging according to AJCC/UICC TNM criteria for positive oropharyngeal carcinomas. Cancer. 2016 Jul 1; 122(13): 2021-2030. doi: 10.1002/cncr.30021. PMID: 27111669.

12.  Ghareeb ER, Dulmage BO, Vargo JA, Balasubramani GK, Beriwal S. Underutilization of Mohs Micrographic Surgery for Less Common Cutaneous Malignancies in the United States. Dermatologic Surgery. 2016 Ma; 42(5): 653-662. PMID:27054447.

13.  Glaser SM, Mandish SF, Gill BS, Balasubramani GK, Clump DA, Beriwal S. Anaplastic thyroid cancer: Prognostic factors, patterns of care, and overall survival. Head Neck. 2016 Apr; 38 Suppl 1: E2083-E2090. doi: 10.1002/hed.24384. PMID: 26894506.

14.  Karen M. Xu, Beant S. Gill, Balasubramani GK, Paniti Sukumvanich, Joseph L. Kelley, Sushil Beriwal: Utilization and Role of Adjuvant Radiotherapy and Chemotherapy for Uterine Clear Cell Carcinoma A National Cancer Data Base Analysis. International Journal of Gynecological Cancer, 2016 Mar; 26(3): 472-482. PMID: 2682583

15.  Glaser SM, Vargo JA, Balasubramani GK, Beriwal S. Surveillance and Radiation Therapy for Stage I Seminoma-Have We Learned From the Evidence? Int J Radiat Oncol Biol Phys. 2016 Jan 1;94(1):75-84. PMID:26700704

16.  Shein SL, Ferguson NM, Kochanek PM, Bayir H, Clark RS, Fink EL, Tyler-Kabara EC, Wisniewski SR, Tian Y, Balasubramani GK, Bell MJ.  Effectiveness of Pharmacological Therapies for Intracranial Hypertension in Children With Severe Traumatic Brain Injury-Results From an Automated Data Collection System Time-Synched to Drug Administration. Pediatr Crit Care Med. 2016 Mar; 17(3): 236-245. PMID: 26673840

17.  Amity CL, Schlenk EA, Gold KN, Eckels MM, Mohan N, Balasubramani GK, Wisniewski SR, Levesque MC, Starz TW. Agreement of Physicians and Nurses Performing Tender and Swollen Joint Counts in Rheumatoid Arthritis. J Clin Rheumatol. 2016 Jan;22(1):30-34. PMID: 26513306.

18.  Gill BS, Vargo JA, Pai SS, Balasubramani GK, Beriwal S. Management Trends and Outcomes for Stage I to II Mantle Cell Lymphoma Using the National Cancer Data Base: Ascertaining the Ideal Treatment Paradigm. Int J Radiat Oncol Biol Phys. 2015 Nov 1;93(3):668-76. PMID:  26461009.

19.  Vargo JA, Gill BS, Balasubramani GK, Beriwal S. Treatment Selection and Survival Outcomes in Early-Stage Diffuse Large B-Cell Lymphoma: Do We Still Need Consolidative Radiotherapy? J Clin Oncol. 2015 Nov 10; 33(32): 3710-3717. PMID: 26261253.

20.  Vargo JA, Gill BS, Balasubramani GK, Beriwal S. What is the optimal management of early-stage low-grade follicular lymphoma in the modern era?  Cancer. 2015 Sep 15; 121(18): 3325-3334. PMID: 26042364.

21.  Nowalk MP, Balasubramani GK, Schaffer M, Lieberman M, Eng H, Kyle S, Wisniewski S, Zimmerman RK, Middleton DB. Intention to receive influenza vaccine after an acute respiratory illness. Am J Health Behav. 2015Jul; 39(4): 573-581. PMID:26018106.

22.  Zimmerman RK, Rinaldo CR, Nowalk MP, Balasubramani GK, Moehling KK, Bullotta A, Eng HF, Raviotta JM, Sax TM, Wisniewski S. Viral infections in outpatients with medically attended acute respiratory illness during the 2012-2013 influenza season. BMC Infect Dis. 2015 Feb 22;15(1):87. PMID:25887948.

23.  Gill BS, Bernard ME, Lin JF, Balasubramani GK, Rajagopalan MS, Sukumvanich P, Krivak TC, Olawaiye AB, Kelley JL, Beriwal S. Impact of adjuvant chemotherapy with radiation for node-positive vulvar cancer: A National Cancer Data Base (NCDB) analysis. Gynecol Oncol. 2015 Jun;137(3):365-72. PMID:25868965.

24.  Simonetti JA, Gingo MR, Kingsley L, Kessinger C, Lucht L, Balasubramani GK, Leader JK, Huang L, Greenblatt RM, Dermand J, Kleerup EC, Morris A. Pulmonary Function in HIV-Infected Recreational Drug Users in the Era of Anti-Retroviral Therapy. J AIDS Clin Res. 2014 Nov;5(11). pii: 365. PMID: 25664201.

25.  Chin KH, Bell MJ, Wisniewski SR, Balasubramani GK, Kochanek PM, Beers SR, Brown SD, Adelson PD; Pediatric Traumatic Brain Injury Consortium: Hypothermia Investigators. Effect of administration of neuromuscular blocking agents in children with severe traumatic brain injury on acute complication rates and outcomes: a secondary analysis from a randomized, controlled trial of therapeutic hypothermia. Pediatr Crit Care Med. 2015 May;16(4):352-8. PMID: 25599147

26.  Zimmerman RK, Rinaldo CR, Nowalk MP, Balasubramani GK, Thompson MG, Bullotta A, Susick M, Wisniewski S. Detection of influenza virus infection using two PCR methods. Adv Virol. 2014;2014:274679. PMID: 25574169

27.  Gingo MR, Balasubramani GK, Rice TB, Kingsley L, Kleerup EC, Detels R, Seaberg EC, Greenblatt RM, Holman S, Huang L, Sutton SH, Bertolet M, Morris A: Pulmonary symptoms and diagnoses are associated with HIV in the MACS and WIHS cohorts. BMC Pulmonary Medicine. 2014; 14(1):75. PMID:24884738.

28.  Zimmerman RK, Rinaldo CR, Nowalk MP, Balasubramani GK, Thompson MG, Moehling KK, Bullotta A, Wisniewski SR: Influenza and other respiratory virus infections in outpatients with medically attended acute respiratory infection during the 2011-12 influenza season. Influenza and Other Respiratory Viruses. 2014; 8(4): 397-405. PMID: 24852890.

29.  Ellen B. Dennehy, Lauren B. Marangell, James M Martinez, Balasubramani GK, Stephen R. Wisniewski: Clinical and functional outcomes of patients who experience partial response to citalopram: Secondary analysis of STAR*D. Journal of Psychiatric Practice. 2014; 20: 178-187. PMID:24847991.

30.  Adelson PD, Wisniewski SR, Beca J, Brown SD, Bell M, Muizelaar JP, Okada P, Beers SR, Balasubramani GK, Hirtz D; Paediatric Traumatic Brain Injury Consortium.( 2013). Comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3, randomised controlled trial. Lancet Neurology. 12(6):546-53. PMID:23664370.

31.  Trivedi MH, Morris DW, Wisniewski SR, Lesser I, Nierenberg AA, Daly E, Kurian BT, Gaynes BN, Balasubramani GK, Rush AJ.(2013): Increase in work productivity of depressed individuals with improvement in depressive symptom severity. Am J Psychiatry. 170(6):633-41. PMID:23558394.

32.  Gingo MR, Balasubramani GK, Kingsley L, Rinaldo CR Jr, Alden CB, Detels R, Greenblatt RM, Hessol NA, Holman S, Huang L, Kleerup EC, Phair J, Sutton SH, Seaberg EC, Margolick JB, Wisniewski SR, Morris A.(2013): The impact of HAART on the respiratory complications of HIV infection: longitudinal trends in the MACS and WIHS cohorts. PLoS One. 8(3):1-9. PMID:23554932.

33.  Dording CM, LaRocca RA, Hails KA, Vitolo OV, Wisniewski SR, Balasubramani GK, Trivedi M, Fava M, Mischoulon D.(2013): The effect of sildenafil on quality of life. Ann Clin Psychiatry. 25(1):3-10. PMID:23376864.

34.  Sung SC, Wisniewski SR, Balasubramani GK, Zisook S, Kurian B, Warden D, Trivedi MH, Rush AJ.(2012): Does  early-onset chronic or recurrent major depression impact outcomes with antidepressant medications? A CO-MED Trial Report. Psychological Medicine, Dec.11:1-16. PMID: 23228340.

35.  Farabaugh A, Alpert J, Wisniewski SR, Otto MW, Fava M, Baer L, Perlis R, Friedman E, Nyer M,  BitranS, Balasubramani GK, Inamori A, Trivedi M, Thase ME.(2012): Cognitive therapy for anxious depression in STAR*D: What have we learned?. Journal of Affective Disorder,142(1-3):213-8. PMID:22877961.

36.  Davis LL, Pilkinton P, Wisniewski SR, Trivedi MH, Gaynes BN, Howland RH, Zisook S,Balasubramani GK, Fava M, Rush AJ.(2012): Effect of concurrent substance use disorder on the effectiveness of single and combination antidepressant medications for the treatment of major depression: an exploratory analysis of a single-blind randomized trial. Depression and Anxiety, 29(2):111-22. PMID:22495941

37.  Chan HN, Rush AJ, Nierenberg AA, Trivedi M, Wisniewski SR, Balasubramani GK, Friedman ES, Gaynes BN, Davis L, Morris D, Fava M.(2012): Correlates and outcomes of depressed out-patients with greater and fewer anxious symptoms: a CO-MED report. International Journal of Neuropsychopharmacology, 15(10):1387-99. PMID:22129562

38.  Rush AJ, Wisniewski SR, Zisook S, Fava M, Sung SC, Haley CL, Chan HN, Gilmer WS, Warden D, Nierenberg AA, Balasubramani GK, Gaynes BN, Trivedi MH, Hollon SD.(2012): Is prior course of illness relevant to acute or           longer-term outcomes in depressed out-patients? A STAR*D report. Psychological Medicine, 42(6):1131-49. PMID:22008447

39.  Wang HE, Balasubramani GK, Cook LJ, Lave JR, Yealy DM (2011): Medical Conditions associated with out-of-hospital endotracheal intubation. Prehospital Emergency Care, 15: 338-346.

 40.  Balasubramani M, Schreiber EM, Candiello J, Balasubramani GK, Kurtz J, Halfter W. (2010): Molecular interactions in the retinal basement membrane system: A proteomic approach. Matrix Biology, 29(6): 471-483.

41.  Wang HE, Balasubramani GK, Cook LJ, Lave JR, Yealy DM (2010): Out-of-Hospital Endotracheal Intubation Experience and Patient Outcomes. Annals of Emergency Medicine, 55(6): 527-537. e6.

42.  Charlene Bryan, Thomas Songer, Maria Mori Brooks, A.John Rush, Michael E. Thase, Bradley Gaynes, Balasubramani GK, Madhukar H. Trivedi, Maurizio Fava, Stephen R. Wisniewski (2010), The impact of diabetes on depression treatment outcomes. General Hospital Psychiatry, 32(1): 33-41.

43.  Charlene Bryan, Thomas Songer, Maria Mori Brooks, Michael E. Thase, Bradley Gaynes, Michael Klinkman, Balasubramani GK, A. John Rush, Madhukar H. Trivedi, Maurizio Fava, Stephen R. Wisniewski (2009). Do depressed patients with diabetes experience more side effects when treated with Citalopram than their counterparts without diabetes? A STAR*D study. The Primary Care Companion of the Journal of Clinical Psychiatry, 11(5):186-196.

44.  Lori L. Davis, Stephen R. Wisniewski, Robert H. Howland, Madhukar H. Trivedi, Mustafa M.Husain, Maurizio Fava, Patrick J. McGrath, Balasubramani GK, Diane Warden, A. John Rush (2010): Does Comorbid Substance Use Disorder Impair Recovery from Major Depression with SSRI Treatment? An Analysis of the STAR*D Level One Treatment Outcomes. Drug and Alcohol Dependence, 107: 161-170.

45.  Richard C. Shelton, Steve D.Hollon, Stephen R.Wisniewski, Jonathan E.Alpert, Balasubramani GK, Edward S.Friedman, A.John Rush, Madhukar H.Trivedi, Sheldon H. Preskorn (2009): Factors associated with concomitant psychotropic drug use in the treatment of major depression: A STAR*D report. CNS Spectrum, 14(9): 487-498.

46.  Diane Warden, Madhukar H.Trivedi, Stephen R.Wisniewski, Ira M.Lesser, Jeff Mitchell, Balasubramani GK, Maurizio Fava, Kathy Shores-Wilson, Diane Stegman, A.John Rush (2009): Identifying Risk for attrition during treatment for depression. Psychotherapy and Psychosomatics, 78(6):372-379.

47.  Diane Warden, A.John Rush, Stephen R. Wisniewski, Ira M. Lesser, Michael E. Thase, Balasubramani GK, Kathy Shores-Wilson, Andrew A. Nierenberg, Madhukar H. Trivedi (2009): Income and attrition in the treatment of depression: A STAR*D Report. Depression and Anxiety, 26(7): 622-633.

48.  Edward S. Friedman, Stephen R.Wisniewski, William Gilmer, Andrew Nierenberg, A. John Rush, Maurizio Fava, Sidney Zisook, Balasubramani GK, Madhukar H.Trivedi (2009): Sociodemographic and clinical and treatment  characteristics associated with worsened depression during treatment with Citalopram: Results of the NIMH STAR*D trial. Depression and Anxiety, 26(7): 612-621.

49.  Jonathan W.Stewart, Patrick J. McGrath, Maurizio Fava, Stephen R. Wisniewski, Sidney Zisook, Ian Cook, Andrew A. Nierenberg, Madhukar H. Trivedi, Balasubramani GK, Diane Warden, Ira Lesser, A.John Rush (2010): Do atypical features affect outcome in depressed outpatients treated with Citalopram? International Journal of Neuropsychopharmacology, 13(1):15-30.

50.  David W. Morris, Madhukar H. Trivedi, Maurizio Fava, Stephen R. Wisniewski, Balasubramani GK, Ahsan Y. Khan, Shailesh Jain, A. John Rush (2009): Diurnal mood variation in outpatients with major depressive disorder. Depression and Anxiety, 26(9):851-863.

51.  Mustafa M. Husain, A. John Rush, Stephen R. Wisniewski, Shawn M. McClintock, Maurizio Fava, Andrew A. Nierenberg, Lori Davis, Balasubramani GK, Elizabeth Young,  A. Ari Abala,  Madhukar H. Trivedi (2009): Family history of depression and Therapeutic outcome: Findings from STAR*D. Journal of Clinical Psychiatry, 70(2), 185-195. PMID: 19192454.

52.  Robert H. Howland, A. John Rush, Stephen R. Wisniewski, Madhukar H. Trivedi, Diane Warden, Maurizio Fava, Lori L. Davis, Balasubramani GK, Patrick McGrath, Susan R. Berman (2009): Concurrent anxiety and substance use disorders among outpatients with major depression: Clinical features and effect on treatment outcome. Drug and Alcohol Dependence, 99, 248-260. PMID: 18986774.

53.  Elizabeth A. Young, Susan G. Kornstein, Sheila M. Marcus, Anne T. Harvey, Diane Warden, Stephen R. Wisniewski, Balasubramani GK, Maurizio Fava, Madhukar H. Trivedi, A. John Rush (2009): Sex differences in response to Citalopram: A STAR*D Report. Journal of Psychiatric Research, 43(5), 503-511. PMID: 18752809.

54.  Diane Warden, A.John Rush, Stephen R.Wisniewski, Ira M.Lesser, Susan G.Kronstein, Balasubramani GK, Michael E. Thase, Sheldon H. Preskorn,  Andrew A.Nierenberg, Elizabeth A.Young, Kathy Shores-Wilson, Madhukar H.Trivedi (2008): What predicts attrition in second step medication treatments for depression? A STAR*D Report. The International Journal of Neuropsychopharmacology, 1-15. PMID: 18611293.

55.  Sheila M. Marcus, Kevin B. Kerber, A.John Rush, Stephen R.Wisniewski, Andrew A. Nierenberg, Balasubramani GK, Louise Ritz, Susan Kornstein, Elizabeth A. Young, Madhukar H. Trivedi (2008): Sex differences in depression symptoms in treatment seeking adults: confirmatory analyses from the Sequenced Treatment Alternatives to Relieve Depression study. Comprehensive Psychiatry, 49(3), 238-246. PMID: 18396182.

56.  Bradley N. Gaynes, A.John Rush, Madhukar H. Trivedi,  Stephen R. Wisniewski, Balasubramani GK, Patrick McGrath, Michael Thase, Michael Klinkman,  Andrew A. Nierenberg, William Yates, Maurizio Fava (2008): Primary vs. specialty care outcomes for depressed outpatients managed with measurement based care: Results from STAR*D. Journal of General Internal Medicine, 23(5), 551-560. PMID: 18247097.

57.  Maurizio Fava, A.John Rush, Jonathan E.Alpert, Balasubramani GK, Stephen R.Wisniewski, Cheryl N.Carmin, Melanie M. Biggs, Sidney Zisook, Andrew Leuchter, Robert Howland, Diane Warden, Madhukar H.Trivedi (2008): Difference in treatment outcome in outpatients with anxious vs. non-anxious depression: A STAR*D report. American Journal of Psychiatry, 165(3), 342-351. PMID: 18172020.

58.  David W. Morris, A.John Rush, Shailesh Jain, Maurizio Fava, Stephen R. Wisniewski, Balasubramani GK, Ahsan Y.Khan, Madhukar H. Trivedi (2007): Diurnal mood variation in outpatients with major depressive disorder: Implications for DSM-V, from an analysis of the Sequenced Treatment Alternatives to Relieve Depression Study Data. Journal of Clinical Psychiatry, 68(9), 1339-1347. PMID: 17915971.

59.  Sidney Zisook, Ira Lesser, Jonathan W.Stewart, Stephen R.Wisniewski, Balasubramani GK, Maurizio Fava, William S. Gilmer, Timothy R. Dresselhaus, Michael E. Thase Andrew Nierenberg, Madhukar H. Trivedi, A.John Rush (2007): Effect of Age of onset on the course of major depressive disorder.  American Journal of Psychiatry, 164(10), 1539-1546. PMID: 17898345.

60.  Diane Warden, Madhukar H. Trivedi, Stephen R. Wisniewski, Lori Davis, Andrew A. Nierenberg, Bradley N. Gaynes, Sidney Zisook, Steven D. Hollon, Balasubramani GK,  Robert Howland, Maurizio Fava, Jonathan W. Stewart, A. John Rush(2007): Predictors of attrition during initial (Citalopram) treatment for depression: A STAR*D Report. American Journal of Psychiatry, 164(8), 1189-1197. PMID: 17671281.

61.  Ira M. Lesser, Andrew F. Leuchter, Madhukar H.Trivedi, Lori L.Davis, Stephen R.Wisniewski, Balasubramani GK, Maurizio Fava, A.John Rush (2007): Insured and non-insured depressed outpatients in public and private sectors: How do they compare? Annals of Clinical Psychiatry, 19(2), 73-82. PMID: 17612846. PMID: 17612846.

62.  Bradley N. Gayens, A.John Rush, Madhukar H.Trivedi, Stephen R.Wisniewski, Balasubramani GK, Donald C. Spencer, Timothy Petersen, Michael Klinkman, Diane Warden, Linda Nicholas, Maurizio Fava (2007): Major Depressions in Primary care and Psychiatric care settings are minimally different: A cross-sectional analysis. Annals of Family Medicine, 5(2), 126-134. PMID: 17389536.

63.  Sidney Zisook, A.John Rush, Ira Lesser, Stephen R.Wisniewski, Madhukar H.Trivedi, Mustafa M.Husain, Balasubramani GK, Jonathan E. Alpert, Maurizio Fava (2007): Pre-adult onset vs. adult onset of major depression disorder: A replication study. Acta Psychiatrica Scandinavica, 115(3), 196-205. PMID: 17302619.

64.  Ian A.Cook, Balasubramani GK, Heather Eng, Edward Friedman, Young EA, Jeff Martin, William Nay, Louise Ritz, A. John Rush, Diane Stegman, Madhukar H. Trivedi Stephen R.Wisniewski (2007): Electronic source materials in clinical research: Acceptability and validity of symptom self-rating in depression. Journal of Psychiatric Research, 41(9), 737-743. PMID: 17275840.

65.  Maurizio Fava, A.John Rush, Jonathan E.Alpert, Cheryl N.Carmin, Balasubramani GK, Stephen R.Wisniewski, Madhukar H.Trivedi, Melanie M.Biggs, Kathy Shores-Wilson (2006): What Clinical and Symptom Features Comorbid Disorders Characterize Outpatients with Anxious Major Depressive Disorder: A Replication and Extension. The Canadian Journal of Psychiatry. 51(13), 823-835. PMID: 17195602.

66.  Lori L. Davis, Elizabeth Frazier, Mustafa M.Husain, Diane Warden,  Madhukar H.Trivedi, Maurizio Fava, Paolo Cassano, Patrick J. McGrath, Balasubramani GK, Stephen R.Wisniewski, A.John Rush (2006): Substance use disorder comorbidity in major depressive disorder: A confirmatory analysis of the STAR*D cohort. The American Journal on Addictions, 15(4), 278-285. PMID: 16867922.

67.  Cynthia A. Claassen, Madhukar H. Trivedi, A.John Rush, Mustafa M. Husain, Sidney Zisook, Elizabeth Young, Andrew Leuchter, Stephen R. Wisniewski, Balasubramani GK, Jonathan Alpert (2007): Clinical differences among depressed patients with and without a history of suicide attempts: Findings from the STAR*D trial. Journal of Affective Disorder, 97(1-3), 77-84. PMID: 16824617.

68.  Anthony Fabio, Rolf Loeber, Balasubramani GK, Jeffrey Roth, Wenjiang Fu, David Farrington, (2006): Why some generations are more violent than others: Assessment of age, period and cohort effects. American Journal of Epidemiology, 164(2), 151-160. PMID: 16775045.

69.  Stephen R.Wisniewski, A.John Rush, Balasubramani GK, Madhukar H.Trivedi, Andrew  A. Nierenberg for the STAR*D Investigators (2006): Self-Rated Global Measure of the frequency, intensity and burden of side effects. Journal of Psychiatric Practice,12(2), 71-79. PMID: 16728903.

70.  Andrew A. Nierenberg, Madhukar H.Trivedi, Maurizio Fava, Melanie M.Biggs, Kathy Shores-Wilson, Stephen R.Wisniewski, Balasubramani GK, A.John Rush (2007): Family history of mood disorder and characteristics of major depressive disorder: A STAR*D (Sequenced Treatment Alternatives to Relieve Depression) study. Journal of Psychiatric Research, 41(3-4), 214-221. PMID: 16690084.

71.  Madhukar H.Trivedi, A.John Rush, Stephen R.Wisniewski,  Andrew A. Nierenberg, Diane Warden,  Louise Ritz, Grayson Norquist, Robert H. Howland,  Barry LebowitzPatrick J. McGrath, Kathy Shores-Wilson, Melanie M.Biggs, Balasubramani GK, Maurizio Fava, for the STAR*D study team (2006): Evaluation of outcomes with Citalopram for depression using measurement based care in STAR*D: Implications for clinical research and practice. American Journal of Psychiatry, 163(1), 28-40. PMID: 16390886.

72.  Mustafa M.Husain, A.John Rush, Harold A. Sackeim, Stephen R.Wisniewski, Shawn M. McClintock, Nicoletta Craven, Joel Holiner, Jeff R. Mitchell, Balasubramani GK Robert Hauger (2005): Age Related Characteristics of Depression: A Preliminary STAR*D Report. American Journal of Geriatric Psychiatry, 13(10), 852-860. PMID: 16223963.

73.  Ira M. Lesser, Andrew F. Leuchter,  Madhukar H. Trivedi, Lori L. Davis,  Stephen R. Wisniewski,  Balasubramani GK, Timothy Petersen, Diane Stegman,  A. John Rush  (2005): Characteristics of insured and non-insured outpatients with depression in STAR*D. Psychiatric Services, 56(8), 995-1004. PMID: 16088018.

74.  Jon S.Novick, Jonathan W.Stewart, Stephen R.Wisniewski, Ian A.Cook, Radmila Manev, Andrew A. Nierenberg, Jerrold Rosenbaum, Kathy Shores-Wilson, Balasubramani GK, Melanie M.Biggs, Sid Zisook, A.John Rush (2005): Clinical and Demographic features of Atypical Depression in outpatients with Major Depressive Disorder: Preliminary findings from STAR*D. The Journal of Clinical Psychiatry, 66(8), 1002-1011. PMID: 16086615.

75.  Sheila M. Marcus, Elizabeth A.Young, Kevin B. Kerber, Susan Kornstein, Amy H. Farabaugh, Jeff Mitchell, Stephen R.Wisniewski, Balasubramani GK, Madhukar H.Trivedi, A.John Rush (2005): Gender Differences at Baseline: Findings from the STAR*D study. Journal of Affective Disorder, 87(2-3), 141-150. PMID: 15982748.

76.  Balasubramani GK, Stephen R.Wisniewski, Hongwei Zhang, Heather F. Eng (2005): Development of an efficient SASâ Macro to perform permutation test for two independent samples. Computer Methods and Programs in Biomedicine, 79(2), 179-187. PMID: 15904990.

77.  Bradley N. Gaynes, A. John Rush, Madhukar Trivedi, Stephen R. Wisniewski, Balasubramani GK, Donald C. Spencer, Timothy Petersen, Michael Klinkman, Diane Warden, Robert K.Schneider, Daniel B.Castro, Robert N. Golden (2005): A direct comparison of presenting characteristics of depressed outpatients from primary vs. specialty care settings: preliminary findings from the STAR*D clinical trial. General Hospital Psychiatry, 27(2), 87-96. PMID: 15763119.

78.  Lori L.Davis, A.John Rush, Stephen R.Wisniewski, Kayla Rice, Paolo Cassano, Michele E.Jewell, Melanie M.Biggs, Kathy Shores-Wilson, Balasubramani GK, Mustafa M.Husain, Federic M.Quitkin, Patrick J.McGarth (2005): Substance use disorder comorbidity in major depressive disorder: an exploratory analysis of the Sequenced Treatment Alternatives to Relieve Depression cohort. Comprehensive Psychiatry, 46(2), 81-89. PMID: 15723023.

79.  Maurizio Fava , Jonathan E.Alpert, Cheryl N.Carmin, Stephen R.Wisniewski, Madhukar H.Trivedi, Melanie M.Biggs, Kathy Shores-Wilson, Don Morgan, Terry Schwartz, Balasubramani GK, A.John Rush (2004): Clinical correlates and symptom patterns of anxious depression among  patients with major depressive disorder in STAR*D. Psychological Medicine, 34(7), 1299-1308. PMID:15697056.

80.  Sidney Zisook, A.John Rush, Ari Albala, Jonathan Alpert, Balasubramani GK, Maurizio Fava, Mustafa Husain, Harold Sackheim, Madhukar H. Trivedi, Stephen R.Wisniewski (2004): Factors that differentiate early vs. later onset of Major Depression Disorder. Psychiatry Research, 129(2), 127-140. PMID:15590040.

81.  Suresh Chandra, K., Sampath,S, Balasubramani GK (1992). Markov sampling for finite population. Biometrika, 79(1), 210-213.

 

 

 

 

Balasubramani  K Goundappa
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